9CPN

Structural basis of BAK sequestration by MCL-1 and consequences for apoptosis initiation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0042981	biological_process	regulation of apoptotic process
A	0055085	biological_process	transmembrane transport
B	0008643	biological_process	carbohydrate transport
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0042981	biological_process	regulation of apoptotic process
B	0055085	biological_process	transmembrane transport
C	0008643	biological_process	carbohydrate transport
C	0015144	molecular_function	carbohydrate transmembrane transporter activity
C	0042981	biological_process	regulation of apoptotic process
C	0055085	biological_process	transmembrane transport
D	0008643	biological_process	carbohydrate transport
D	0015144	molecular_function	carbohydrate transmembrane transporter activity
D	0042981	biological_process	regulation of apoptotic process
D	0055085	biological_process	transmembrane transport
E	0042981	biological_process	regulation of apoptotic process
F	0042981	biological_process	regulation of apoptotic process
G	0042981	biological_process	regulation of apoptotic process
H	0042981	biological_process	regulation of apoptotic process

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO911-ASN928

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site_id	PS01080
Number of Residues	20
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA

Chain	Residue	Details
A	VAL1253-ALA1272

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site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV

Chain	Residue	Details
A	TRP1305-VAL1316

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site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN

Chain	Residue	Details
A	ALA1209-ASN1223
E	VAL74-ARG88

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	Motif: {"description":"BH3"}

Chain

Residue

Details

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