9CPL

The ubiquitin-associated domain of human thirty-eight negative kinase 1, fused to the 2TEL crystallization chaperone via a 2-glycine linker

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	2TEL/Non-receptor tyrosine-protein kinase TNK1 fusion protein	polymer	251	29092.8	1	UniProt (P41212) UniProt (Q13470) Pfam (PF02198)	Homo sapiens (human)
2	B (A)	FORMIC ACID	non-polymer		46.0	1	Chemie (FMT)
3	C (A)	water	water		18.0	17	Chemie (HOH)

Sequence modifications

A: 13 - 90 (UniProt: P41212)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 46	Arg 80	engineered mutation
Glu 78	Val 112	engineered mutation

A: 98 - 172 (UniProt: P41212)

PDB	External Database	Details
Pro 91	-	linker
Gly 92	-	linker
Gly 93	-	linker
Gly 94	-	linker
Gly 95	-	linker
Ser 96	-	linker
Thr 97	-	linker
Ser 131	Arg 80	engineered mutation
Gly 173	-	linker
Gly 174	-	linker

A: 175 - 251 (UniProt: Q13470)

PDB	External Database	Details
Ala 195	Cys 610	engineered mutation
Ala 229	Cys 644	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29092.8
Non-Polymers*	Number of molecules	1
	Total formula weight	46.0
All*	Total formula weight	29138.9

*Water molecules are not included.