9CI3
Structure of the LRRK2/14-3-3 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, B) | 14-3-3 protein gamma | polymer | 265 | 30436.8 | 2 | UniProt (P61981) Pfam (PF00244) | Homo sapiens (human) | Protein kinase C inhibitor protein 1,KCIP-1 |
| 2 | C (A) | Leucine-rich repeat serine/threonine-protein kinase 2 | polymer | 2562 | 290652.2 | 1 | UniProt (Q5S007) Pfam (PF13855) Pfam (PF08477) Pfam (PF16095) Pfam (PF00069) | Homo sapiens (human) | Dardarin |
| 3 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) |
Sequence modifications
C, B: 1 - 247 (UniProt: P61981)
A: 1 - 2527 (UniProt: Q5S007)
| PDB | External Database | Details |
|---|---|---|
| Met -17 | - | initiating methionine |
| Gly -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -34 | - | initiating methionine |
| Gly -33 | - | expression tag |
| Ser -32 | - | expression tag |
| Asp -31 | - | expression tag |
| Tyr -30 | - | expression tag |
| Lys -29 | - | expression tag |
| Asp -28 | - | expression tag |
| His -27 | - | expression tag |
| Asp -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Asp -24 | - | expression tag |
| Tyr -23 | - | expression tag |
| Lys -22 | - | expression tag |
| Asp -21 | - | expression tag |
| His -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Ile -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Lys -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| His 50 | Arg 50 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 351525.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 443.2 | |
| All* | Total formula weight | 351969.0 |
