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9CFC

Cryo-EM structure of human kidney V-ATPase state 2

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(0)
V-type proton ATPase 21 kDa proteolipid subunitpolymer20521418.21UniProt (Q99437)Homo sapiens (human)V-ATPase 21 kDa proteolipid subunit,Vacuolar proton pump 21 kDa proteolipid subunit,hATPL
2B, C, D, E, F...
(1, 2, 3, 4, 5...)
V-type proton ATPase 16 kDa proteolipid subunitpolymer15515743.79UniProt (P27449)Homo sapiens (human)V-ATPase 16 kDa proteolipid subunit,Vacuolar proton pump 16 kDa proteolipid subunit
3K, L, M
(A, B, C)
V-type proton ATPase catalytic subunit Apolymer61768379.93UniProt (P38606)Homo sapiens (human)V-ATPase subunit A,V-ATPase 69 kDa subunit,Vacuolar ATPase isoform VA68,Vacuolar proton pump subunit alpha
4N, O, P
(D, E, F)
V-type proton ATPase subunit B, brain isoformpolymer51156561.53UniProt (P21281)Homo sapiens (human)V-ATPase subunit B 2,Endomembrane proton pump 58 kDa subunit,HO57,Vacuolar proton pump subunit B 2
5Q
(G)
V-type proton ATPase subunit Dpolymer24728311.91UniProt (Q9Y5K8)Homo sapiens (human)V-ATPase subunit D,V-ATPase 28 kDa accessory protein,Vacuolar proton pump subunit D
6R, S, T
(H, I, J)
V-type proton ATPase subunit E 1polymer22626183.33UniProt (P36543)Homo sapiens (human)V-ATPase subunit E 1,V-ATPase 31 kDa subunit,p31,Vacuolar proton pump subunit E 1
7U, V, W
(K, L, M)
V-type proton ATPase subunit G 1polymer11813781.53UniProt (O75348)Homo sapiens (human)V-ATPase subunit G 1,V-ATPase 13 kDa subunit 1,Vacuolar proton pump subunit G 1,Vacuolar proton pump subunit M16
8X
(N)
V-type proton ATPase subunit Fpolymer11913388.21UniProt (Q16864)Homo sapiens (human)V-ATPase subunit F,V-ATPase 14 kDa subunit,Vacuolar proton pump subunit F
9Y
(Q)
V-type proton ATPase subunit d 1polymer35140369.91UniProt (P61421)Homo sapiens (human)V-ATPase subunit d 1,32 kDa accessory protein,V-ATPase 40 kDa accessory protein,V-ATPase AC39 subunit,p39,Vacuolar proton pump subunit d 1
10Z
(R)
V-type proton ATPase 116 kDa subunit a isoform 1polymer83796512.41UniProt (Q93050)Homo sapiens (human)V-ATPase 116 kDa isoform a1,Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit,Vacuolar adenosine triphosphatase subunit Ac116,Vacuolar proton pump subunit 1,Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
11AA
(S)
V-type proton ATPase subunit e 1polymer819380.31UniProt (O15342)Homo sapiens (human)V-ATPase subunit e 1,V-ATPase 9.2 kDa membrane accessory protein,V-ATPase M9.2 subunit,Vacuolar proton pump subunit e 1
12BA
(T)
Ribonuclease kappapolymer13715435.21UniProt (Q6P5S7)Homo sapiens (human)RNase kappa
13CA
(U)
V-type proton ATPase subunit S1polymer47052067.51UniProt (Q15904)Homo sapiens (human)V-ATPase subunit S1,Protein XAP-3,V-ATPase Ac45 subunit,V-ATPase S1 accessory protein,Vacuolar proton pump subunit S1
14DA
(V)
Renin receptorpolymer35039045.91UniProt (O75787)Homo sapiens (human)ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,ER-localized type I transmembrane adapter,Embryonic liver differentiation factor 10,N14F,Renin/prorenin receptor,Vacuolar ATP synthase membrane sector-associated protein M8-9,V-ATPase M8.9 subunit
15EA
(B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains30
Total formula weight952341.3
Non-Polymers*Number of molecules1
Total formula weight427.2
All*Total formula weight952768.5
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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