9C48
Cryo-EM structure of the full-length human P2X4 receptor in the ATP-bound desensitized state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C (A, B, C) | P2X purinoceptor 4 | polymer | 388 | 43415.0 | 3 | UniProt (Q99571) Pfam (PF00864) | Homo sapiens (human) | P2X4,ATP receptor,Purinergic receptor |
2 | D, E, G, H, J... (D, E, G, H, J...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
3 | F, I, L (F, I, L) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
4 | M, S, X (A, B, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
5 | AA, N, O, P, T... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
6 | Q, R, W (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
7 | BA, CA, DA (A, B, C) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 130245.0 | |
Branched | Number of molecules | 9 |
Total formula weight | 4306.0 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 3585.3 | |
All* | Total formula weight | 138136.4 |