9C3E
TCR - CD3 complex bound to HLA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TCRa | polymer | 272 | 30214.0 | 1 | Homo sapiens (human) | ||
| 2 | B | TCRb (EGFP fusion) | polymer | 557 | 62121.9 | 1 | Homo sapiens (human) | ||
| 3 | D | T-cell surface glycoprotein CD3 delta chain | polymer | 125 | 13836.0 | 1 | UniProt (P04234) Pfam (PF16680) In PDB | Homo sapiens (human) | T-cell receptor T3 delta chain |
| 4 | E, F | T-cell surface glycoprotein CD3 epsilon chain | polymer | 207 | 23174.2 | 2 | UniProt (P07766) Pfam (PF16681) Pfam (PF02189) In PDB | Homo sapiens (human) | |
| 5 | G | T-cell surface glycoprotein CD3 gamma chain | polymer | 194 | 22041.1 | 1 | UniProt (P09693) Pfam (PF16680) Pfam (PF02189) In PDB | Homo sapiens (human) | T-cell receptor T3 gamma chain |
| 6 | X, Y | T-cell surface glycoprotein CD3 zeta chain | polymer | 164 | 18723.4 | 2 | UniProt (P20963) Pfam (PF02189) Pfam (PF11628) In PDB | Homo sapiens (human) | T-cell receptor T3 zeta chain |
| 7 | H | Cancer/testis antigen 1,Beta-2-microglobulin,MHC class I antigen | polymer | 593 | 62221.3 | 1 | UniProt (P78358) UniProt (P61769) UniProt (H9BNV4) Pfam (PF07654) Pfam (PF00129) In PDB | Homo sapiens (human) | Autoimmunogenic cancer/testis antigen NY-ESO-1,Cancer/testis antigen 6.1,CT6.1,L antigen family member 2,LAGE-2 |
| 8 | N | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 9 | A, B, D, G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 10 | G, Y | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) |
Sequence modifications
G: 1 - 182 (UniProt: P09693)
H: 1 - 9 (UniProt: P78358)
H: 121 - 218 (UniProt: P61769)
H: 326 - 593 (UniProt: H9BNV4)
| PDB | External Database | Details |
|---|---|---|
| Val 183 | - | expression tag |
| Glu 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
| His 192 | - | expression tag |
| Val 193 | - | expression tag |
| Asp 194 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 9 | Cys 165 | engineered mutation |
| Unk 11 | - | linker |
| Unk 12 | - | linker |
| Unk 13 | - | linker |
| Unk 14 | - | linker |
| Unk 15 | - | linker |
| Unk 16 | - | linker |
| Unk 17 | - | linker |
| Unk 18 | - | linker |
| Unk 19 | - | linker |
| Unk 20 | - | linker |
| Unk 21 | - | linker |
| Unk 22 | - | linker |
| Unk 23 | - | linker |
| Unk 24 | - | linker |
| Unk 25 | - | linker |
| Unk 26 | - | linker |
| Unk 27 | - | linker |
| Unk 28 | - | linker |
| Unk 29 | - | linker |
| Unk 30 | - | linker |
| Unk 31 | - | linker |
| Unk 32 | - | linker |
| Unk 33 | - | linker |
| Unk 34 | - | linker |
| Unk 35 | - | linker |
| Unk 36 | - | linker |
| Unk 37 | - | linker |
| Unk 38 | - | linker |
| Unk 39 | - | linker |
| Unk 40 | - | linker |
| Unk 41 | - | linker |
| Unk 42 | - | linker |
| Unk 43 | - | linker |
| Unk 44 | - | linker |
| Unk 45 | - | linker |
| Unk 46 | - | linker |
| Unk 47 | - | linker |
| Unk 48 | - | linker |
| Unk 49 | - | linker |
| Unk 50 | - | linker |
| Unk 51 | - | linker |
| Unk 52 | - | linker |
| Unk 53 | - | linker |
| Unk 54 | - | linker |
| Unk 55 | - | linker |
| Unk 56 | - | linker |
| Unk 57 | - | linker |
| Unk 58 | - | linker |
| Unk 59 | - | linker |
| Unk 60 | - | linker |
| Unk 61 | - | linker |
| Unk 62 | - | linker |
| Unk 63 | - | linker |
| Unk 64 | - | linker |
| Unk 65 | - | linker |
| Unk 66 | - | linker |
| Unk 67 | - | linker |
| Unk 68 | - | linker |
| Unk 69 | - | linker |
| Unk 70 | - | linker |
| Unk 71 | - | linker |
| Unk 72 | - | linker |
| Unk 73 | - | linker |
| Unk 74 | - | linker |
| Unk 75 | - | linker |
| Unk 76 | - | linker |
| Unk 77 | - | linker |
| Unk 78 | - | linker |
| Unk 79 | - | linker |
| Unk 80 | - | linker |
| Unk 81 | - | linker |
| Unk 82 | - | linker |
| Unk 83 | - | linker |
| Unk 84 | - | linker |
| Unk 85 | - | linker |
| Unk 86 | - | linker |
| Unk 87 | - | linker |
| Unk 88 | - | linker |
| Unk 89 | - | linker |
| Unk 90 | - | linker |
| Unk 91 | - | linker |
| Unk 92 | - | linker |
| Unk 93 | - | linker |
| Unk 94 | - | linker |
| Unk 95 | - | linker |
| Unk 96 | - | linker |
| Unk 97 | - | linker |
| Unk 98 | - | linker |
| Unk 99 | - | linker |
| Unk 100 | - | linker |
| Unk 101 | - | linker |
| Unk 102 | - | linker |
| Unk 103 | - | linker |
| Unk 104 | - | linker |
| Unk 105 | - | linker |
| Unk 106 | - | linker |
| Unk 107 | - | linker |
| Unk 108 | - | linker |
| Unk 109 | - | linker |
| Unk 110 | - | linker |
| Unk 111 | - | linker |
| Unk 112 | - | linker |
| Unk 113 | - | linker |
| Unk 114 | - | linker |
| Unk 115 | - | linker |
| Unk 116 | - | linker |
| Unk 117 | - | linker |
| Unk 118 | - | linker |
| Unk 119 | - | linker |
| Unk 120 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 218 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 219 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 220 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 221 | - | linker |
| Unk 222 | - | linker |
| Unk 222 | - | linker |
| Unk 222 | - | linker |
| Unk 222 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 274229.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2543.0 | |
| All* | Total formula weight | 277359.2 |
