9C3C
Cryo-EM structure of native dystrophin-glycoprotein complex (DGC)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-dystroglycan | polymer | 624 | 67623.7 | 1 | UniProt (Q28685) Pfam (PF05345) Pfam (PF18424) | Oryctolagus cuniculus (rabbit) | Beta-DG |
| 2 | B (B) | Beta-dystroglycan | polymer | 145 | 15714.1 | 1 | UniProt (Q28685) Pfam (PF05454) | Oryctolagus cuniculus (rabbit) | Beta-DG |
| 3 | C (D) | Dystrophin | polymer | 3696 | 427942.8 | 1 | Pfam (PF00435) Pfam (PF00397) Pfam (PF09068) Pfam (PF09069) Pfam (PF00569) UniProt (by SIFTS) (G1T8Y6) | Oryctolagus cuniculus (rabbit) | |
| 4 | D (a) | Alpha-sarcoglycan | polymer | 326 | 35969.0 | 1 | UniProt (Q28686) Pfam (PF05510) Pfam (PF20989) | Oryctolagus cuniculus (rabbit) | Alpha-SG,50 kDa dystrophin-associated glycoprotein,50DAG,Adhalin,Dystroglycan-2 |
| 5 | E (b) | Beta-sarcoglycan | polymer | 318 | 34768.7 | 1 | UniProt (Q28635) Pfam (PF04790) | Oryctolagus cuniculus (rabbit) | Beta-SG |
| 6 | F (d) | Sarcoglycan delta | polymer | 289 | 32142.3 | 1 | UniProt (G1SGL0) Pfam (PF04790) | Oryctolagus cuniculus (rabbit) | |
| 7 | G (g) | Gamma-sarcoglycan | polymer | 291 | 32005.5 | 1 | UniProt (Q28646) Pfam (PF04790) | Oryctolagus cuniculus (rabbit) | |
| 8 | H (n) | Sarcospan | polymer | 238 | 26058.6 | 1 | UniProt (P82352) Pfam (PF04103) | Oryctolagus cuniculus (rabbit) | |
| 9 | I (V) | Dystrobrevin | polymer | 818 | 92647.1 | 1 | Pfam (PF09069) Pfam (PF00569) Pfam (PF09068) UniProt (by SIFTS) (A0A5F9C316) | Oryctolagus cuniculus (rabbit) | |
| 10 | J, K, L, M, N... (H, K, O, R, C...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 7 | In PDB GlyTouCan (G15407YE) | |||
| 11 | Q (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 12 | R, S (A, a) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 764871.9 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 4530.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 769844.5 |
