9C1Q
Crystal structure of the WDR domain of human DCAF1 in complex with OICR-39512 compound
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DDB1- and CUL4-associated factor 1 | polymer | 315 | 35592.9 | 1 | UniProt (Q9Y4B6) In PDB | Homo sapiens (human) | HIV-1 Vpr-binding protein,VprBP,Serine/threonine-protein kinase VPRBP,Vpr-interacting protein |
| 2 | A | (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-(3-methoxyprop-1-yn-1-yl)-1H-pyrrole-3-carboxamide | non-polymer | 506.3 | 1 | Chemie (A1ATT) | |||
| 3 | A | UNKNOWN ATOM OR ION | non-polymer | 23.0 | 4 | Chemie (UNX) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A: 1077 - 1390 (UniProt: Q9Y4B6)
| PDB | External Database | Details |
|---|---|---|
| Gly 1076 | - | expression tag |
| Ala 1077 | Phe 1077 | engineered mutation |
| Ala 1079 | Arg 1079 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35592.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 786.1 | |
| All* | Total formula weight | 36379.0 |
