9C13

XMAP215 TOG5 interaction with GMPCPP tubulin lattice

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, D)	Tubulin beta-2B chain	polymer	445	49999.9	2	UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953)	Bos taurus (domestic cattle)
2	C, D (A, C)	Tubulin alpha chain	polymer	451	50188.4	2	UniProt (F2Z4C1) Pfam (PF00091) Pfam (PF03953)	Bos taurus (domestic cattle)
3	E (E)	Cytoskeleton-associated protein 5-A,Cytoskeleton-associated protein 5-A,Green fluorescent protein	polymer	541	61740.7	1	UniProt (Q9PT63) Pfam (PF21041)	Xenopus laevis (African clawed frog)	Microtubule-associated protein 215 kDa,XMAP215
4	F, H (B, D)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	2	Chemie (G2P)
5	G, I, K, M (B, D, A, C)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	J, L (A, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)

Sequence modifications

B, D: 1 - 445 (UniProt: Q6B856)

PDB	External Database	Details
Gly 440	Glu 440	conflict
Glu 441	Gly 441	conflict

A, C: 1 - 451 (UniProt: F2Z4C1)

PDB	External Database	Details
Thr 94	Ser 94	conflict
Ile 122	Val 122	conflict
Ile 231	Met 231	conflict
Gly 232	Ser 232	conflict
Ile 384	Val 384	conflict
Val 435	Ser 435	conflict
Gly 436	Phe 436	conflict
Val 437	Leu 437	conflict
Asp 438	Arg 438	conflict
Ser 439	Pro 439	conflict
Glu 441	Arg 441	conflict
Gly 442	Thr 442	conflict
Glu 443	Trp 443	conflict
Gly 444	Leu 444	conflict
Glu 445	Pro 445	conflict
Glu 446	Leu 446	conflict
Glu 447	Arg 447	conflict
Gly 448	Arg 448	conflict
Glu 449	Ile 449	conflict
Glu 450	Met 450	conflict
Tyr 451	Arg 451	conflict

E: 1191 - 1461 (UniProt: Q9PT63)

PDB	External Database	Details
Met 1190	-	initiating methionine

E: 1462 - 1730 (PDB: 9C13)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	262117.3
Non-Polymers*	Number of molecules	8
	Total formula weight	2186.0
All*	Total formula weight	264303.3

*Water molecules are not included.