9BWT
human sodium chloride cotransporter NCC S344E in the phosphorylation state and in complex with hydrochlorothiazide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Solute carrier family 12 member 3 | polymer | 1020 | 113406.7 | 2 | UniProt (J3QSS1) Pfam (PF08403) Pfam (PF00324) Pfam (PF03522) | Homo sapiens (human) | |
| 2 | C, E (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 3 | D (A) | 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide | non-polymer | 297.7 | 1 | Chemie (HCZ) | |||
| 4 | F (A) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 1020 (UniProt: J3QSS1)
| PDB | External Database | Details |
|---|---|---|
| Glu 344 | Ser 344 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 226813.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1312.1 | |
| All* | Total formula weight | 228125.5 |
