9BS9

Local refinement of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (R)	Soluble cytochrome b562,D(2) dopamine receptor	polymer	588	67234.6	1	UniProt (P0ABE7) UniProt (P14416) Pfam (PF00001)	Escherichia coli	Cytochrome b-562,Dopamine D2 receptor
2	B (R)	(8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide	non-polymer		323.4	1	Chemie (7LD)

Sequence modifications

R: -116 - -12 (UniProt: P0ABE7)

PDB	External Database	Details
Asp -144	-	expression tag
Tyr -143	-	expression tag
Lys -142	-	expression tag
Asp -141	-	expression tag
Asp -140	-	expression tag
Asp -139	-	expression tag
Asp -138	-	expression tag
Ala -137	-	expression tag
Lys -136	-	expression tag
Leu -135	-	expression tag
Gln -134	-	expression tag
Thr -133	-	expression tag
Met -132	-	expression tag
His -131	-	expression tag
His -130	-	expression tag
His -129	-	expression tag
His -128	-	expression tag
His -127	-	expression tag
His -126	-	expression tag
His -125	-	expression tag
His -124	-	expression tag
His -123	-	expression tag
His -122	-	expression tag
His -121	-	expression tag
His -120	-	expression tag
His -119	-	expression tag
His -118	-	expression tag
His -117	-	expression tag
Trp -110	Met 29	conflict
Ile -15	His 124	conflict
Leu -11	-	linker
Ala -10	-	linker
Ser -9	-	linker
Glu -8	-	linker
Asn -7	-	linker
Leu -6	-	linker
Tyr -5	-	linker
Phe -4	-	linker
Gln -3	-	linker
Gly -2	-	linker
Gly -1	-	linker
Thr 0	-	linker

R: 1 - 443 (UniProt: P14416)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	67234.6
Non-Polymers*	Number of molecules	1
	Total formula weight	323.4
All*	Total formula weight	67558.0

*Water molecules are not included.