9BOX

Room-temperature X-ray structure of human mitochondrial serine hydroxymethyltransferase (hSHMT2) with PLP-glycine external aldimine and 5-formyltetrahydrofolate (folinic acid)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Serine hydroxymethyltransferase, mitochondrial	polymer	462	51329.5	4	UniProt (P34897) Pfam (PF00464)	Homo sapiens (human)	SHMT,Glycine hydroxymethyltransferase,Serine methylase
2	E, G, I, K (A, B, C, D)	(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)glycine	non-polymer		304.2	4	Chemie (A1AQW)
3	F, H, J, L (A, B, C, D)	N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid	non-polymer		473.4	4	Chemie (FFO)
4	M, N, O, P (A, B, C, D)	water	water		18.0	765	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	205317.8
Non-Polymers*	Number of molecules	8
	Total formula weight	3110.5
All*	Total formula weight	208428.3

*Water molecules are not included.