9BOX
Room-temperature X-ray structure of human mitochondrial serine hydroxymethyltransferase (hSHMT2) with PLP-glycine external aldimine and 5-formyltetrahydrofolate (folinic acid)
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00096 |
| Number of Residues | 17 |
| Details | SHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DIvTTTTHKTLrGARSG |
| Chain | Residue | Details |
| A | ASP272-GLY288 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS103 | |
| B | LYS181 | |
| B | LYS196 | |
| B | LYS297 | |
| B | LYS356 | |
| B | LYS464 | |
| B | LYS469 | |
| B | LYS474 | |
| C | LYS103 | |
| C | LYS181 | |
| C | LYS196 | |
| A | LYS181 | |
| C | LYS297 | |
| C | LYS356 | |
| C | LYS464 | |
| C | LYS469 | |
| C | LYS474 | |
| D | LYS103 | |
| D | LYS181 | |
| D | LYS196 | |
| D | LYS297 | |
| D | LYS356 | |
| A | LYS196 | |
| D | LYS464 | |
| D | LYS469 | |
| D | LYS474 | |
| A | LYS297 | |
| A | LYS356 | |
| A | LYS464 | |
| A | LYS469 | |
| A | LYS474 | |
| B | LYS103 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:29180469 |
| Chain | Residue | Details |
| A | LYS280 | |
| B | LYS280 | |
| C | LYS280 | |
| D | LYS280 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER470 | |
| B | SER470 | |
| C | SER470 | |
| D | SER470 |
