9BLR
Human SCNN1D-SCNN1B-SCNN1G ENaC trimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 1 of Amiloride-sensitive sodium channel subunit delta | polymer | 638 | 70273.8 | 1 | UniProt (P51172) Pfam (PF00858) | Homo sapiens (human) | Delta-NaCH,Epithelial Na(+) channel subunit delta,Delta-ENaC,ENaCD,Nonvoltage-gated sodium channel 1 subunit delta,SCNED |
| 2 | B (B) | Amiloride-sensitive sodium channel subunit beta | polymer | 640 | 72696.8 | 1 | UniProt (P51168) Pfam (PF00858) | Homo sapiens (human) | Beta-NaCH,Epithelial Na(+) channel subunit beta,Beta-ENaC,ENaCB,Nonvoltage-gated sodium channel 1 subunit beta,SCNEB |
| 3 | C (C) | Amiloride-sensitive sodium channel subunit gamma | polymer | 649 | 74202.7 | 1 | UniProt (P51170) Pfam (PF00858) | Homo sapiens (human) | Epithelial Na(+) channel subunit gamma,ENaCG,Gamma-ENaC,Gamma-NaCH,Nonvoltage-gated sodium channel 1 subunit gamma,SCNEG |
| 4 | D, F, G (E, D, I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | H, I, J, K, L... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A: 1 - 638 (UniProt: P51172)
B: 1 - 640 (UniProt: P51168)
C: 1 - 649 (UniProt: P51170)
| PDB | External Database | Details |
|---|---|---|
| Ala 64 | Cys 64 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 30 | Cys 30 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 33 | Cys 33 | engineered mutation |
| Ala 41 | Cys 41 | engineered mutation |
| Ala 138 | Arg 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 217173.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2184.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 220684.6 |
