9BJK
Inactive mu opioid receptor bound to Nb6, naloxone and NAM
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (N) | kappa opioid receptor Nanobody 6 | polymer | 133 | 14730.3 | 1 | Lama glama | ||
| 2 | B (R) | Mu-type opioid receptor | polymer | 426 | 47920.7 | 1 | UniProt (P42866) Pfam (PF00001) | Mus musculus (house mouse) | M-OR-1,MOR-1 |
| 3 | C (R) | Naloxone | non-polymer | 327.4 | 1 | Chemie (A1APV) PubChem (4425) PubChem (10064) PubChem (5284596) PubChem (5390107) PubChem (5491858) PubChem (5702090) PubChem (6321250) PubChem (6545909) PubChem (6918998) PubChem (11957637) PubChem (13303869) PubChem (13303870) PubChem (13303871) PubChem (13303872) PubChem (13303874) PubChem (13303875) PubChem (13303879) PubChem (13303883) PubChem (13303884) PubChem (16395294) PubChem (16682422) PubChem (18530270) PubChem (23786505) PubChem (42606788) PubChem (186822) PubChem (667494) PubChem (51691054) PubChem (9818787) PubChem (13303876) PubChem (58647324) PubChem (66624200) PubChem (68336375) PubChem (71774987) PubChem (89727402) PubChem (98185014) PubChem (117753977) PubChem (126538501) PubChem (129035763) PubChem (155086808) PubChem (161235492) PubChem (167122378) | |||
| 4 | D (R) | Nalpha-[({(1M)-1-[5-(benzyloxy)pyridin-3-yl]naphthalen-2-yl}sulfanyl)acetyl]-3-methoxy-N,4-dimethyl-L-phenylalaninamide | non-polymer | 605.7 | 1 | Chemie (A1APU) PubChem (171642066) PubChem (171642081) PubChem (171642088) |
Sequence modifications
R: 6 - 398 (UniProt: P42866)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Lys -18 | - | expression tag |
| Thr -17 | - | expression tag |
| Ile -16 | - | expression tag |
| Ile -15 | - | expression tag |
| Ala -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Tyr -11 | - | expression tag |
| Ile -10 | - | expression tag |
| Phe -9 | - | expression tag |
| Cys -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Tyr -2 | - | expression tag |
| Lys -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Asp 1 | - | expression tag |
| Asp 2 | - | expression tag |
| Asp 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Met 5 | - | expression tag |
| Leu 264 | Met 264 | engineered mutation |
| Arg 269 | Lys 269 | engineered mutation |
| Asp 399 | - | expression tag |
| Ile 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
| His 406 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62651.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 933.1 | |
| All* | Total formula weight | 63584.1 |
