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9BIT

Cryo-EM structure of the mammalian peptide transporter PepT2 bound to cloxacillin, pose 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Solute carrier family 15 member 2polymer73882477.81UniProt (Q63424)
Pfam (PF00854)
Rattus norvegicus (Norway rat)Kidney H(+)/peptide cotransporter,Oligopeptide transporter,kidney isoform,Peptide transporter 2
2B
(B)
nanobodypolymer13114494.21Lama glama
3C
(A)
CLOXACILLINnon-polymer435.91Chemie (CXN)
Sequence modifications
A: 1 - 729 (UniProt: Q63424)
PDBExternal DatabaseDetails
Val 730-expression tag
Glu 731-expression tag
Gly 732-expression tag
Glu 733-expression tag
Asn 734-expression tag
Leu 735-expression tag
Tyr 736-expression tag
Phe 737-expression tag
Gln 738-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight96971.9
Non-Polymers*Number of molecules1
Total formula weight435.9
All*Total formula weight97407.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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