Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

9BG4

Tri-complex of Compound-2, KRAS G12V, and CypA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
GTPase KRaspolymer17019400.92UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2C, D
(C, D)
Peptidyl-prolyl cis-trans isomerase Apolymer16618123.62UniProt (P62937)
Pfam (PF00160)
Homo sapiens (human)PPIase A,Cyclophilin A,Cyclosporin A-binding protein,Rotamase A
3E, H
(A, B)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.22Chemie (GNP)
4F, I
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
5G, J
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
6K, L
(C, D)
(2R)-N-[(1P,8S,10S,14S,21M)-22-ethyl-21-{2-[(1R)-1-methoxyethyl]pyridin-3-yl}-18,18-dimethyl-9,15-dioxo-16-oxa-10,22,28-triazapentacyclo[18.5.2.1~2,6~.1~10,14~.0~23,27~]nonacosa-1(25),2(29),3,5,20,23,26-heptaen-8-yl]-3-methyl-2-(N-methylacetamido)butanamide (non-preferred name)non-polymer779.02Chemie (A1AOG)
7M, N, O, P
(A, B, C, D)
waterwater18.01057Chemie (HOH)
Sequence modifications
A, B: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Ser 0-expression tag
Val 12Gly 12engineered mutation
C, D: 1 - 165 (UniProt: P62937)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight75049.0
Non-Polymers*Number of molecules8
Total formula weight2721.9
All*Total formula weight77770.9
*Water molecules are not included.

238895

PDB entries from 2025-07-16

PDB statisticsPDBj update infoContact PDBjnumon