9BCX
Cryo-EM structure of the S. cerevisiae ORC-Cdc6-Mcm2-7-DNA complex with a fully closed Mcm2-Mcm5 DNA entry gate
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (2) | DNA replication licensing factor MCM2 | polymer | 868 | 98911.5 | 1 | UniProt (P29469) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Saccharomyces cerevisiae (brewer's yeast) | Minichromosome maintenance protein 2 |
| 2 | B (3) | DNA replication licensing factor MCM3 | polymer | 971 | 107653.5 | 1 | UniProt (A0A8H8ULI2) Pfam (PF22207) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) UniProt (by SIFTS) (P24279) | Saccharomyces cerevisiae (brewer's yeast) | |
| 3 | C (5) | DNA replication licensing factor MCM5 | polymer | 775 | 86505.7 | 1 | UniProt (A0A6A5PUY8) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933) UniProt (by SIFTS) (P29496) | Saccharomyces cerevisiae (brewer's yeast) | |
| 4 | D (4) | DNA replication licensing factor MCM4 | polymer | 933 | 105138.4 | 1 | UniProt (A0A8H4BU27) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21128) UniProt (by SIFTS) (P30665) | Saccharomyces cerevisiae (brewer's yeast) | |
| 5 | E (6) | DNA replication licensing factor MCM6 | polymer | 1017 | 113110.2 | 1 | UniProt (P53091) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263) | Saccharomyces cerevisiae (brewer's yeast) | Minichromosome maintenance protein 6 |
| 6 | F (7) | DNA replication licensing factor MCM7 | polymer | 845 | 95049.9 | 1 | UniProt (P38132) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Saccharomyces cerevisiae (brewer's yeast) | Cell division control protein 47, Minichromosome maintenance protein 7 |
| 7 | G (B) | Origin recognition complex subunit 1 | polymer | 914 | 104546.2 | 1 | UniProt (P54784) Pfam (PF01426) Pfam (PF00004) Pfam (PF17872) Pfam (PF21312) | Saccharomyces cerevisiae (brewer's yeast) | Origin recognition complex 120 kDa subunit |
| 8 | H (C) | Origin recognition complex subunit 2 | polymer | 620 | 71342.2 | 1 | UniProt (P32833) Pfam (PF04084) | Saccharomyces cerevisiae (brewer's yeast) | Origin recognition complex 71 kDa subunit |
| 9 | I (D) | Origin recognition complex subunit 3 | polymer | 616 | 72161.8 | 1 | UniProt (P54790) Pfam (PF07034) Pfam (PF18137) | Saccharomyces cerevisiae (brewer's yeast) | Origin recognition complex 62 kDa subunit |
| 10 | J (E) | Origin recognition complex subunit 4 | polymer | 529 | 60772.2 | 1 | UniProt (P54791) Pfam (PF14629) | Saccharomyces cerevisiae (brewer's yeast) | Origin recognition complex 56 kDa subunit |
| 11 | K (F) | Origin recognition complex subunit 5 | polymer | 479 | 55347.2 | 1 | UniProt (P50874) Pfam (PF13191) Pfam (PF21639) Pfam (PF14630) | Saccharomyces cerevisiae (brewer's yeast) | Origin recognition complex 53 kDa subunit |
| 12 | L (G) | Origin recognition complex subunit 6 | polymer | 435 | 50369.5 | 1 | UniProt (P38826) Pfam (PF05460) | Saccharomyces cerevisiae (brewer's yeast) | ACS-associated protein 1,Origin recognition complex 50 kDa subunit |
| 13 | M (I) | Cell division control protein 6 | polymer | 513 | 58112.4 | 1 | UniProt (P09119) Pfam (PF13401) Pfam (PF22606) Pfam (PF09079) | Saccharomyces cerevisiae (brewer's yeast) | |
| 14 | N (8) | TAH11 isoform 1 | polymer | 604 | 68486.1 | 1 | UniProt (A0A8H4C095) Pfam (PF16679) UniProt (by SIFTS) (P47112) | Saccharomyces cerevisiae (brewer's yeast) | |
| 15 | O (O) | DNA (39-MER) | polymer | 39 | 11967.7 | 1 | synthetic construct | ||
| 16 | P (P) | DNA (39-MER) | polymer | 39 | 12035.8 | 1 | synthetic construct | ||
| 17 | Q, S, U (B, E, F) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
| 18 | R, T, V, W (B, E, F, I) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 1171510.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1618.8 | |
| All* | Total formula weight | 1173128.9 |
