9B7J
Cryo-EM structure of human dynactin complex bound to Chlamydia effector Dre1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Alpha-centractin | polymer | 376 | 42670.7 | 8 | UniProt (P61163) Pfam (PF00022) | Homo sapiens (human) | Centractin,ARP1,Actin-RPV,Centrosome-associated actin homolog |
| 2 | H (H) | Actin, cytoplasmic 1 | polymer | 375 | 41782.7 | 1 | UniProt (P60709) Pfam (PF00022) | Homo sapiens (human) | Beta-actin |
| 3 | J (J) | Actin-related protein 10 | polymer | 417 | 46360.9 | 1 | UniProt (Q9NZ32) Pfam (PF00022) | Homo sapiens (human) | Actin-related protein 11,hARP11 |
| 4 | K (K) | Dynactin subunit 4 | polymer | 460 | 52409.0 | 1 | UniProt (Q9UJW0) Pfam (PF05502) | Homo sapiens (human) | Dyn4,Dynactin subunit p62 |
| 5 | L (L) | Dynactin subunit 5 | polymer | 182 | 20150.5 | 1 | UniProt (Q9BTE1) Pfam (PF21711) | Homo sapiens (human) | Dynactin subunit p25 |
| 6 | M (M) | Dynactin subunit 6 | polymer | 190 | 20769.0 | 1 | UniProt (O00399) | Homo sapiens (human) | Dynactin subunit p27,Protein WS-3 |
| 7 | N (N) | F-actin-capping protein subunit alpha-1 | polymer | 286 | 32964.7 | 1 | UniProt (P52907) Pfam (PF01267) | Homo sapiens (human) | CapZ alpha-1 |
| 8 | O (O) | F-actin-capping protein subunit beta | polymer | 272 | 30669.8 | 1 | UniProt (P47756) Pfam (PF01115) | Homo sapiens (human) | CapZ beta |
| 9 | P, Q, V, W (P, Q, p, q) | Dynactin subunit 2 | polymer | 401 | 44285.9 | 4 | UniProt (Q13561) Pfam (PF04912) | Homo sapiens (human) | 50 kDa dynein-associated polypeptide,Dynactin complex 50 kDa subunit,DCTN-50,p50 dynamitin |
| 10 | R, X (R, r) | Dynactin subunit 3 | polymer | 186 | 21145.4 | 2 | UniProt (O75935) Pfam (PF07426) | Homo sapiens (human) | Dynactin complex subunit 22 kDa subunit,p22 |
| 11 | S (S) | Dynactin subunit 1 | polymer | 1278 | 141920.6 | 1 | UniProt (Q14203) Pfam (PF01302) Pfam (PF12455) | Homo sapiens (human) | 150 kDa dynein-associated polypeptide,DAP-150,DP-150,p135,p150-glued |
| 12 | T (T) | Dynactin subunit 1, p150-glued | polymer | 83 | 7081.7 | 1 | Homo sapiens | ||
| 13 | U (U) | Dynactin subunit 2, p50 dynamitin | polymer | 87 | 7422.1 | 1 | Homo sapiens | ||
| 14 | Y (s) | Dynactin subunit 1 | polymer | 1278 | 141892.5 | 1 | UniProt (Q14203) Pfam (PF01302) Pfam (PF12455) | Homo sapiens (human) | 150 kDa dynein-associated polypeptide,DAP-150,DP-150,p135,p150-glued |
| 15 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 8 | Chemie (ADP) | |||
| 16 | GA (H) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 17 | IA, JA, KA (K) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
S: 1 - 1286 (UniProt: Q14203)
| PDB | External Database | Details |
|---|---|---|
| Asp 1282 | Ser 1274 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 25 |
| Total formula weight | 1104223.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4120.0 | |
| All* | Total formula weight | 1108343.4 |
