9B7J

Cryo-EM structure of human dynactin complex bound to Chlamydia effector Dre1

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005813	cellular_component	centrosome
A	0005815	cellular_component	microtubule organizing center
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005869	cellular_component	dynactin complex
A	0005875	cellular_component	microtubule associated complex
A	0005938	cellular_component	cell cortex
A	0007010	biological_process	cytoskeleton organization
A	0016192	biological_process	vesicle-mediated transport
A	0070062	cellular_component	extracellular exosome
B	0000166	molecular_function	nucleotide binding
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005813	cellular_component	centrosome
B	0005815	cellular_component	microtubule organizing center
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005869	cellular_component	dynactin complex
B	0005875	cellular_component	microtubule associated complex
B	0005938	cellular_component	cell cortex
B	0007010	biological_process	cytoskeleton organization
B	0016192	biological_process	vesicle-mediated transport
B	0070062	cellular_component	extracellular exosome
C	0000166	molecular_function	nucleotide binding
C	0005200	molecular_function	structural constituent of cytoskeleton
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005813	cellular_component	centrosome
C	0005815	cellular_component	microtubule organizing center
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0005869	cellular_component	dynactin complex
C	0005875	cellular_component	microtubule associated complex
C	0005938	cellular_component	cell cortex
C	0007010	biological_process	cytoskeleton organization
C	0016192	biological_process	vesicle-mediated transport
C	0070062	cellular_component	extracellular exosome
D	0000166	molecular_function	nucleotide binding
D	0005200	molecular_function	structural constituent of cytoskeleton
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005813	cellular_component	centrosome
D	0005815	cellular_component	microtubule organizing center
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005869	cellular_component	dynactin complex
D	0005875	cellular_component	microtubule associated complex
D	0005938	cellular_component	cell cortex
D	0007010	biological_process	cytoskeleton organization
D	0016192	biological_process	vesicle-mediated transport
D	0070062	cellular_component	extracellular exosome
E	0000166	molecular_function	nucleotide binding
E	0005200	molecular_function	structural constituent of cytoskeleton
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005815	cellular_component	microtubule organizing center
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0005869	cellular_component	dynactin complex
E	0005875	cellular_component	microtubule associated complex
E	0005938	cellular_component	cell cortex
E	0007010	biological_process	cytoskeleton organization
E	0016192	biological_process	vesicle-mediated transport
E	0070062	cellular_component	extracellular exosome
F	0000166	molecular_function	nucleotide binding
F	0005200	molecular_function	structural constituent of cytoskeleton
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005813	cellular_component	centrosome
F	0005815	cellular_component	microtubule organizing center
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0005869	cellular_component	dynactin complex
F	0005875	cellular_component	microtubule associated complex
F	0005938	cellular_component	cell cortex
F	0007010	biological_process	cytoskeleton organization
F	0016192	biological_process	vesicle-mediated transport
F	0070062	cellular_component	extracellular exosome
G	0000166	molecular_function	nucleotide binding
G	0005200	molecular_function	structural constituent of cytoskeleton
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005813	cellular_component	centrosome
G	0005815	cellular_component	microtubule organizing center
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0005869	cellular_component	dynactin complex
G	0005875	cellular_component	microtubule associated complex
G	0005938	cellular_component	cell cortex
G	0007010	biological_process	cytoskeleton organization
G	0016192	biological_process	vesicle-mediated transport
G	0070062	cellular_component	extracellular exosome
H	0000166	molecular_function	nucleotide binding
H	0000776	cellular_component	kinetochore
H	0000785	cellular_component	chromatin
H	0001738	biological_process	morphogenesis of a polarized epithelium
H	0005200	molecular_function	structural constituent of cytoskeleton
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005615	cellular_component	extracellular space
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005856	cellular_component	cytoskeleton
H	0005884	cellular_component	actin filament
H	0005886	cellular_component	plasma membrane
H	0005903	cellular_component	brush border
H	0005911	cellular_component	cell-cell junction
H	0005912	cellular_component	adherens junction
H	0005925	cellular_component	focal adhesion
H	0006338	biological_process	chromatin remodeling
H	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0007010	biological_process	cytoskeleton organization
H	0007020	biological_process	microtubule nucleation
H	0007163	biological_process	establishment or maintenance of cell polarity
H	0007409	biological_process	axonogenesis
H	0008284	biological_process	positive regulation of cell population proliferation
H	0015629	cellular_component	actin cytoskeleton
H	0016020	cellular_component	membrane
H	0016363	cellular_component	nuclear matrix
H	0016787	molecular_function	hydrolase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0019894	molecular_function	kinesin binding
H	0019901	molecular_function	protein kinase binding
H	0021762	biological_process	substantia nigra development
H	0030027	cellular_component	lamellipodium
H	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
H	0030235	molecular_function	nitric-oxide synthase regulator activity
H	0030424	cellular_component	axon
H	0030863	cellular_component	cortical cytoskeleton
H	0030957	molecular_function	Tat protein binding
H	0031492	molecular_function	nucleosomal DNA binding
H	0031982	cellular_component	vesicle
H	0032991	cellular_component	protein-containing complex
H	0034333	biological_process	adherens junction assembly
H	0035267	cellular_component	NuA4 histone acetyltransferase complex
H	0035633	biological_process	maintenance of blood-brain barrier
H	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
H	0042802	molecular_function	identical protein binding
H	0042981	biological_process	regulation of apoptotic process
H	0043296	cellular_component	apical junction complex
H	0044305	cellular_component	calyx of Held
H	0045176	biological_process	apical protein localization
H	0045202	cellular_component	synapse
H	0045582	biological_process	positive regulation of T cell differentiation
H	0045596	biological_process	negative regulation of cell differentiation
H	0045597	biological_process	positive regulation of cell differentiation
H	0045663	biological_process	positive regulation of myoblast differentiation
H	0045893	biological_process	positive regulation of DNA-templated transcription
H	0048156	molecular_function	tau protein binding
H	0048870	biological_process	cell motility
H	0050998	molecular_function	nitric-oxide synthase binding
H	0051621	biological_process	regulation of norepinephrine uptake
H	0051623	biological_process	positive regulation of norepinephrine uptake
H	0051726	biological_process	regulation of cell cycle
H	0070062	cellular_component	extracellular exosome
H	0070160	cellular_component	tight junction
H	0070316	biological_process	regulation of G0 to G1 transition
H	0070527	biological_process	platelet aggregation
H	0071896	biological_process	protein localization to adherens junction
H	0072562	cellular_component	blood microparticle
H	0072749	biological_process	cellular response to cytochalasin B
H	0097433	cellular_component	dense body
H	0098685	cellular_component	Schaffer collateral - CA1 synapse
H	0098793	cellular_component	presynapse
H	0098871	cellular_component	postsynaptic actin cytoskeleton
H	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
H	0098974	biological_process	postsynaptic actin cytoskeleton organization
H	0098978	cellular_component	glutamatergic synapse
H	0141108	molecular_function	transporter regulator activity
H	0150111	biological_process	regulation of transepithelial transport
H	1900242	biological_process	regulation of synaptic vesicle endocytosis
H	1902459	biological_process	positive regulation of stem cell population maintenance
H	1903076	biological_process	regulation of protein localization to plasma membrane
H	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
H	1990904	cellular_component	ribonucleoprotein complex
H	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
H	2000779	biological_process	regulation of double-strand break repair
H	2000781	biological_process	positive regulation of double-strand break repair
H	2000819	biological_process	regulation of nucleotide-excision repair
I	0000166	molecular_function	nucleotide binding
I	0005200	molecular_function	structural constituent of cytoskeleton
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005813	cellular_component	centrosome
I	0005815	cellular_component	microtubule organizing center
I	0005829	cellular_component	cytosol
I	0005856	cellular_component	cytoskeleton
I	0005869	cellular_component	dynactin complex
I	0005875	cellular_component	microtubule associated complex
I	0005938	cellular_component	cell cortex
I	0007010	biological_process	cytoskeleton organization
I	0016192	biological_process	vesicle-mediated transport
I	0070062	cellular_component	extracellular exosome
J	0005200	molecular_function	structural constituent of cytoskeleton
J	0005515	molecular_function	protein binding
J	0005576	cellular_component	extracellular region
J	0005634	cellular_component	nucleus
J	0005829	cellular_component	cytosol
J	0005856	cellular_component	cytoskeleton
J	0005869	cellular_component	dynactin complex
J	0007010	biological_process	cytoskeleton organization
J	0035578	cellular_component	azurophil granule lumen
J	0098958	biological_process	retrograde axonal transport of mitochondrion
J	1904115	cellular_component	axon cytoplasm
J	1904813	cellular_component	ficolin-1-rich granule lumen
K	0000776	cellular_component	kinetochore
K	0000922	cellular_component	spindle pole
K	0001725	cellular_component	stress fiber
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005813	cellular_component	centrosome
K	0005829	cellular_component	cytosol
K	0005856	cellular_component	cytoskeleton
K	0005868	cellular_component	cytoplasmic dynein complex
K	0005869	cellular_component	dynactin complex
K	0005925	cellular_component	focal adhesion
K	0005938	cellular_component	cell cortex
K	0030017	cellular_component	sarcomere
L	0000776	cellular_component	kinetochore
L	0005515	molecular_function	protein binding
L	0005813	cellular_component	centrosome
L	0005829	cellular_component	cytosol
L	0005856	cellular_component	cytoskeleton
L	0005869	cellular_component	dynactin complex
M	0000776	cellular_component	kinetochore
M	0005515	molecular_function	protein binding
M	0005813	cellular_component	centrosome
M	0005829	cellular_component	cytosol
M	0005856	cellular_component	cytoskeleton
M	0005869	cellular_component	dynactin complex
M	0007052	biological_process	mitotic spindle organization
M	0015630	cellular_component	microtubule cytoskeleton
M	0070840	molecular_function	dynein complex binding
N	0003779	molecular_function	actin binding
N	0005515	molecular_function	protein binding
N	0005576	cellular_component	extracellular region
N	0005829	cellular_component	cytosol
N	0005856	cellular_component	cytoskeleton
N	0008290	cellular_component	F-actin capping protein complex
N	0015629	cellular_component	actin cytoskeleton
N	0030036	biological_process	actin cytoskeleton organization
N	0030863	cellular_component	cortical cytoskeleton
N	0034329	biological_process	cell junction assembly
N	0045296	molecular_function	cadherin binding
N	0051015	molecular_function	actin filament binding
N	0051016	biological_process	barbed-end actin filament capping
N	0051693	biological_process	actin filament capping
N	0065003	biological_process	protein-containing complex assembly
N	0070062	cellular_component	extracellular exosome
N	0071203	cellular_component	WASH complex
O	0003779	molecular_function	actin binding
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005856	cellular_component	cytoskeleton
O	0005903	cellular_component	brush border
O	0008290	cellular_component	F-actin capping protein complex
O	0014069	cellular_component	postsynaptic density
O	0015629	cellular_component	actin cytoskeleton
O	0016020	cellular_component	membrane
O	0030017	cellular_component	sarcomere
O	0030027	cellular_component	lamellipodium
O	0030036	biological_process	actin cytoskeleton organization
O	0030863	cellular_component	cortical cytoskeleton
O	0045296	molecular_function	cadherin binding
O	0051016	biological_process	barbed-end actin filament capping
O	0051693	biological_process	actin filament capping
O	0070062	cellular_component	extracellular exosome
O	0071203	cellular_component	WASH complex
O	0098685	cellular_component	Schaffer collateral - CA1 synapse
O	0098686	cellular_component	hippocampal mossy fiber to CA3 synapse
O	0120212	cellular_component	sperm head-tail coupling apparatus
p	0000776	cellular_component	kinetochore
p	0005515	molecular_function	protein binding
p	0005737	cellular_component	cytoplasm
p	0005813	cellular_component	centrosome
p	0005829	cellular_component	cytosol
p	0005856	cellular_component	cytoskeleton
p	0005869	cellular_component	dynactin complex
p	0005874	cellular_component	microtubule
p	0007017	biological_process	microtubule-based process
p	0007052	biological_process	mitotic spindle organization
p	0007080	biological_process	mitotic metaphase chromosome alignment
p	0016020	cellular_component	membrane
p	0019901	molecular_function	protein kinase binding
p	0030286	cellular_component	dynein complex
p	0030426	cellular_component	growth cone
p	0030507	molecular_function	spectrin binding
p	0031982	cellular_component	vesicle
p	0036064	cellular_component	ciliary basal body
p	0042802	molecular_function	identical protein binding
p	0070062	cellular_component	extracellular exosome
p	0071539	biological_process	protein localization to centrosome
P	0000776	cellular_component	kinetochore
P	0005515	molecular_function	protein binding
P	0005737	cellular_component	cytoplasm
P	0005813	cellular_component	centrosome
P	0005829	cellular_component	cytosol
P	0005856	cellular_component	cytoskeleton
P	0005869	cellular_component	dynactin complex
P	0005874	cellular_component	microtubule
P	0007017	biological_process	microtubule-based process
P	0007052	biological_process	mitotic spindle organization
P	0007080	biological_process	mitotic metaphase chromosome alignment
P	0016020	cellular_component	membrane
P	0019901	molecular_function	protein kinase binding
P	0030286	cellular_component	dynein complex
P	0030426	cellular_component	growth cone
P	0030507	molecular_function	spectrin binding
P	0031982	cellular_component	vesicle
P	0036064	cellular_component	ciliary basal body
P	0042802	molecular_function	identical protein binding
P	0070062	cellular_component	extracellular exosome
P	0071539	biological_process	protein localization to centrosome
q	0000776	cellular_component	kinetochore
q	0005515	molecular_function	protein binding
q	0005737	cellular_component	cytoplasm
q	0005813	cellular_component	centrosome
q	0005829	cellular_component	cytosol
q	0005856	cellular_component	cytoskeleton
q	0005869	cellular_component	dynactin complex
q	0005874	cellular_component	microtubule
q	0007017	biological_process	microtubule-based process
q	0007052	biological_process	mitotic spindle organization
q	0007080	biological_process	mitotic metaphase chromosome alignment
q	0016020	cellular_component	membrane
q	0019901	molecular_function	protein kinase binding
q	0030286	cellular_component	dynein complex
q	0030426	cellular_component	growth cone
q	0030507	molecular_function	spectrin binding
q	0031982	cellular_component	vesicle
q	0036064	cellular_component	ciliary basal body
q	0042802	molecular_function	identical protein binding
q	0070062	cellular_component	extracellular exosome
q	0071539	biological_process	protein localization to centrosome
Q	0000776	cellular_component	kinetochore
Q	0005515	molecular_function	protein binding
Q	0005737	cellular_component	cytoplasm
Q	0005813	cellular_component	centrosome
Q	0005829	cellular_component	cytosol
Q	0005856	cellular_component	cytoskeleton
Q	0005869	cellular_component	dynactin complex
Q	0005874	cellular_component	microtubule
Q	0007017	biological_process	microtubule-based process
Q	0007052	biological_process	mitotic spindle organization
Q	0007080	biological_process	mitotic metaphase chromosome alignment
Q	0016020	cellular_component	membrane
Q	0019901	molecular_function	protein kinase binding
Q	0030286	cellular_component	dynein complex
Q	0030426	cellular_component	growth cone
Q	0030507	molecular_function	spectrin binding
Q	0031982	cellular_component	vesicle
Q	0036064	cellular_component	ciliary basal body
Q	0042802	molecular_function	identical protein binding
Q	0070062	cellular_component	extracellular exosome
Q	0071539	biological_process	protein localization to centrosome
r	0000278	biological_process	mitotic cell cycle
r	0000776	cellular_component	kinetochore
r	0005198	molecular_function	structural molecule activity
r	0005515	molecular_function	protein binding
r	0005737	cellular_component	cytoplasm
r	0005813	cellular_component	centrosome
r	0005819	cellular_component	spindle
r	0005829	cellular_component	cytosol
r	0005869	cellular_component	dynactin complex
r	0005875	cellular_component	microtubule associated complex
r	0030496	cellular_component	midbody
r	0032154	cellular_component	cleavage furrow
r	0048471	cellular_component	perinuclear region of cytoplasm
r	0051301	biological_process	cell division
r	0061640	biological_process	cytoskeleton-dependent cytokinesis
R	0000278	biological_process	mitotic cell cycle
R	0000776	cellular_component	kinetochore
R	0005198	molecular_function	structural molecule activity
R	0005515	molecular_function	protein binding
R	0005737	cellular_component	cytoplasm
R	0005813	cellular_component	centrosome
R	0005819	cellular_component	spindle
R	0005829	cellular_component	cytosol
R	0005869	cellular_component	dynactin complex
R	0005875	cellular_component	microtubule associated complex
R	0030496	cellular_component	midbody
R	0032154	cellular_component	cleavage furrow
R	0048471	cellular_component	perinuclear region of cytoplasm
R	0051301	biological_process	cell division
R	0061640	biological_process	cytoskeleton-dependent cytokinesis
s	0000132	biological_process	establishment of mitotic spindle orientation
s	0000278	biological_process	mitotic cell cycle
s	0000776	cellular_component	kinetochore
s	0000922	cellular_component	spindle pole
s	0005515	molecular_function	protein binding
s	0005635	cellular_component	nuclear envelope
s	0005737	cellular_component	cytoplasm
s	0005813	cellular_component	centrosome
s	0005814	cellular_component	centriole
s	0005819	cellular_component	spindle
s	0005829	cellular_component	cytosol
s	0005856	cellular_component	cytoskeleton
s	0005874	cellular_component	microtubule
s	0005875	cellular_component	microtubule associated complex
s	0005938	cellular_component	cell cortex
s	0007077	biological_process	mitotic nuclear membrane disassembly
s	0007097	biological_process	nuclear migration
s	0007399	biological_process	nervous system development
s	0007528	biological_process	neuromuscular junction development
s	0008017	molecular_function	microtubule binding
s	0010008	cellular_component	endosome membrane
s	0010457	biological_process	centriole-centriole cohesion
s	0015630	cellular_component	microtubule cytoskeleton
s	0015631	molecular_function	tubulin binding
s	0016020	cellular_component	membrane
s	0019901	molecular_function	protein kinase binding
s	0021517	biological_process	ventral spinal cord development
s	0030286	cellular_component	dynein complex
s	0030424	cellular_component	axon
s	0030904	cellular_component	retromer complex
s	0031116	biological_process	positive regulation of microtubule polymerization
s	0031252	cellular_component	cell leading edge
s	0032935	molecular_function	sterol sensor activity
s	0032991	cellular_component	protein-containing complex
s	0034454	biological_process	microtubule anchoring at centrosome
s	0035371	cellular_component	microtubule plus-end
s	0036064	cellular_component	ciliary basal body
s	0042147	biological_process	retrograde transport, endosome to Golgi
s	0042632	biological_process	cholesterol homeostasis
s	0043005	cellular_component	neuron projection
s	0043025	cellular_component	neuronal cell body
s	0045171	cellular_component	intercellular bridge
s	0048156	molecular_function	tau protein binding
s	0050905	biological_process	neuromuscular process
s	0051301	biological_process	cell division
s	0060236	biological_process	regulation of mitotic spindle organization
s	0061744	biological_process	motor behavior
s	0070050	biological_process	neuron cellular homeostasis
s	0090063	biological_process	positive regulation of microtubule nucleation
s	0090120	biological_process	lysosome to ER cholesterol transport
s	0098930	biological_process	axonal transport
s	0099558	biological_process	maintenance of synapse structure
s	0099738	cellular_component	cell cortex region
s	0120103	cellular_component	centriolar subdistal appendage
s	1904398	biological_process	positive regulation of neuromuscular junction development
s	1905515	biological_process	non-motile cilium assembly
s	1990535	biological_process	neuron projection maintenance
S	0000132	biological_process	establishment of mitotic spindle orientation
S	0000278	biological_process	mitotic cell cycle
S	0000776	cellular_component	kinetochore
S	0000922	cellular_component	spindle pole
S	0005515	molecular_function	protein binding
S	0005635	cellular_component	nuclear envelope
S	0005737	cellular_component	cytoplasm
S	0005813	cellular_component	centrosome
S	0005814	cellular_component	centriole
S	0005819	cellular_component	spindle
S	0005829	cellular_component	cytosol
S	0005856	cellular_component	cytoskeleton
S	0005874	cellular_component	microtubule
S	0005875	cellular_component	microtubule associated complex
S	0005938	cellular_component	cell cortex
S	0007077	biological_process	mitotic nuclear membrane disassembly
S	0007097	biological_process	nuclear migration
S	0007399	biological_process	nervous system development
S	0007528	biological_process	neuromuscular junction development
S	0008017	molecular_function	microtubule binding
S	0010008	cellular_component	endosome membrane
S	0010457	biological_process	centriole-centriole cohesion
S	0015630	cellular_component	microtubule cytoskeleton
S	0015631	molecular_function	tubulin binding
S	0016020	cellular_component	membrane
S	0019901	molecular_function	protein kinase binding
S	0021517	biological_process	ventral spinal cord development
S	0030286	cellular_component	dynein complex
S	0030424	cellular_component	axon
S	0030904	cellular_component	retromer complex
S	0031116	biological_process	positive regulation of microtubule polymerization
S	0031252	cellular_component	cell leading edge
S	0032935	molecular_function	sterol sensor activity
S	0032991	cellular_component	protein-containing complex
S	0034454	biological_process	microtubule anchoring at centrosome
S	0035371	cellular_component	microtubule plus-end
S	0036064	cellular_component	ciliary basal body
S	0042147	biological_process	retrograde transport, endosome to Golgi
S	0042632	biological_process	cholesterol homeostasis
S	0043005	cellular_component	neuron projection
S	0043025	cellular_component	neuronal cell body
S	0045171	cellular_component	intercellular bridge
S	0048156	molecular_function	tau protein binding
S	0050905	biological_process	neuromuscular process
S	0051301	biological_process	cell division
S	0060236	biological_process	regulation of mitotic spindle organization
S	0061744	biological_process	motor behavior
S	0070050	biological_process	neuron cellular homeostasis
S	0090063	biological_process	positive regulation of microtubule nucleation
S	0090120	biological_process	lysosome to ER cholesterol transport
S	0098930	biological_process	axonal transport
S	0099558	biological_process	maintenance of synapse structure
S	0099738	cellular_component	cell cortex region
S	0120103	cellular_component	centriolar subdistal appendage
S	1904398	biological_process	positive regulation of neuromuscular junction development
S	1905515	biological_process	non-motile cilium assembly
S	1990535	biological_process	neuron projection maintenance

Functional Information from PROSITE/UniProt

site_id	PS00231
Number of Residues	6
Details	F_ACTIN_CAPPING_BETA F-actin capping protein beta subunit signature. CDYNRD

Chain	Residue	Details
O	CYS62-ASP67

---

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
H	TYR53-GLY63

---

site_id	PS00748
Number of Residues	9
Details	F_ACTIN_CAPPING_A_1 F-actin capping protein alpha subunit signature 1. VHYYEDGNV

Chain	Residue	Details
N	VAL196-VAL204

---

site_id	PS00749
Number of Residues	11
Details	F_ACTIN_CAPPING_A_2 F-actin capping protein alpha subunit signature 2. KaLRRqLPVTR

Chain	Residue	Details
N	LYS256-ARG266

---

site_id	PS00845
Number of Residues	32
Details	CAP_GLY_1 CAP-Gly domain signature. Gatlfatgk..WvGVilDeak....GKNdGTvqGrkYF

Chain	Residue	Details
S	GLY48-PHE79
s	GLY48-PHE79

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
H	TRP356-GLU364
A	TRP357-GLU365

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
H	LEU104-ARG116
A	LEU109-ARG121

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Methionine (R)-sulfoxide","evidences":[{"source":"PubMed","id":"29343822","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"30526847","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30626964","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30785395","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31388018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32503840","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"23673617","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Cross-link: {"description":"(Microbial infection) Isoglutamyl lysine isopeptide (Lys-Glu) (interchain with E-270); by Vibrio toxins RtxA and VgrG1","evidences":[{"source":"PubMed","id":"19015515","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Cross-link: {"description":"(Microbial infection) Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-50); by Vibrio toxins RtxA and VgrG1","evidences":[{"source":"PubMed","id":"19015515","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9QUR2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	209
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15144186","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	5
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q99KJ8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	24
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Ramsay A.","Leung H.Y."]}},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q99KJ8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---