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9B6I

Cryo-EM structure of the avian great tit TRPM8 channel in complex with the antagonist TC-I 2014

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, D, C)
Transient receptor potential cation channel subfamily M member 8polymer1141131966.24UniProt (by SIFTS) (A0A5S8WF66)Parus major (Great Tit)
2E, K, Q, W
(A, B, D, C)
CALCIUM IONnon-polymer40.14Chemie (CA)
PubChem (271)
3BA, F, G, H, J...
(C, A, B, D)
CHOLESTEROL HEMISUCCINATEnon-polymer486.716Chemie (Y01)
PubChem (16219150)
PubChem (22210610)
PubChem (65082)
PubChem (45489984)
PubChem (363416)
PubChem (60078761)
PubChem (500055)
PubChem (73440805)
PubChem (57163942)
PubChem (89891013)
PubChem (99567468)
PubChem (124427194)
PubChem (124897021)
PubChem (124897020)
PubChem (10005657)
PubChem (130340716)
PubChem (99567469)
PubChem (11969853)
PubChem (137392566)
PubChem (137496323)
PubChem (124301053)
PubChem (124302591)
PubChem (124303794)
PubChem (124421343)
PubChem (124427195)
PubChem (13301926)
PubChem (13301927)
PubChem (124914595)
PubChem (124914596)
PubChem (155804219)
PubChem (169132514)
PubChem (131705526)
PubChem (137332121)
PubChem (137496357)
PubChem (146157332)
PubChem (154929912)
PubChem (155199678)
PubChem (156327905)
PubChem (156426247)
PubChem (156516588)
PubChem (166979870)
PubChem (167024614)
PubChem (169132513)
PubChem (170117245)
PubChem (172400028)
4AA, I, O, U
(C, A, B, D)
3-{7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl}-1-oxa-2-azaspiro[4.5]dec-2-enenon-polymer467.44Chemie (T14)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight527864.8
Non-Polymers*Number of molecules24
Total formula weight9817.6
All*Total formula weight537682.4
*Water molecules are not included.

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PDB entries from 2026-05-06

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