9B62
Human RANBP2/RAN(GTP)/RANGAP1-SUMO1/UBC9/CRM1/RAN(GTP) - composite map and model
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Exportin-1 | polymer | 1074 | 123874.8 | 1 | UniProt (O14980) Pfam (PF03810) Pfam (PF08389) Pfam (PF18777) Pfam (PF18784) Pfam (PF18787) Pfam (PF08767) | Homo sapiens (human) | Exp1,Chromosome region maintenance 1 protein homolog |
| 2 | B, F (B, F) | GTP-binding nuclear protein Ran | polymer | 222 | 25012.8 | 2 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 3 | C (C) | SUMO-conjugating enzyme UBC9 | polymer | 161 | 18313.1 | 1 | UniProt (P63279) Pfam (PF00179) | Homo sapiens (human) | RING-type E3 SUMO transferase UBC9,SUMO-protein ligase,Ubiquitin carrier protein 9,Ubiquitin carrier protein I,Ubiquitin-conjugating enzyme E2 I,Ubiquitin-protein ligase I,p18 |
| 4 | D (D) | Small ubiquitin-related modifier 1 | polymer | 101 | 11532.0 | 1 | UniProt (P63165) Pfam (PF11976) | Homo sapiens (human) | SUMO-1,GAP-modifying protein 1,GMP1,SMT3 homolog 3,Sentrin,Ubiquitin-homology domain protein PIC1,Ubiquitin-like protein SMT3C,Smt3C,Ubiquitin-like protein UBL1 |
| 5 | E (E) | E3 SUMO-protein ligase RanBP2 | polymer | 619 | 68399.4 | 1 | UniProt (P49792) Pfam (PF12185) Pfam (PF00638) | Homo sapiens (human) | 358 kDa nucleoporin,Nuclear pore complex protein Nup358,Nucleoporin Nup358,Ran-binding protein 2,RanBP2,p270 |
| 6 | G (G) | Ran GTPase-activating protein 1 | polymer | 591 | 64022.2 | 1 | UniProt (P46060) Pfam (PF13516) Pfam (PF07834) | Homo sapiens (human) | RanGAP1 |
| 7 | H, J (B, F) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 8 | I, K (B, F) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A: 1 - 1071 (UniProt: O14980)
B, F: 1 - 216 (UniProt: P62826)
C: 1 - 158 (UniProt: P63279)
D: 1 - 97 (UniProt: P63165)
E: 2446 - 3060 (UniProt: P49792)
G: 1 - 587 (UniProt: P46060)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Leu 69 | Gln 69 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Pro 94 | Gln 94 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 2442 | - | expression tag |
| Ser 2443 | - | expression tag |
| His 2444 | - | expression tag |
| Met 2445 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 336167.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 337262.0 |
