9B4L
Filament of Tau in complex with D-TLKIVWI, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, AA, B, BA, C... (A, B, C, D, M...) | Microtubule-associated protein tau | polymer | 758 | 79041.6 | 12 | UniProt (P10636) Pfam (PF00418) | Homo sapiens (human) | Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau |
| 2 | CA, DA, E, EA, F... (E, F, G, H, I...) | DTH-DLE-DLY-DIL-DVA-DTR-DIL | polymer | 7 | 872.1 | 24 | synthetic construct | ||
| 3 | KA, LA, MA, NA, OA... (A, C, M, O, 0...) | {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID | non-polymer | 292.2 | 6 | Chemie (EDT) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 36 |
| Total formula weight | 969429.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1753.5 | |
| All* | Total formula weight | 971183.4 |
