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9B4L

Filament of Tau in complex with D-TLKIVWI, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM

Functional Information from GO Data
ChainGOidnamespacecontents
00000226biological_processmicrotubule cytoskeleton organization
00001774biological_processmicroglial cell activation
00003677molecular_functionDNA binding
00003680molecular_functionminor groove of adenine-thymine-rich DNA binding
00003690molecular_functiondouble-stranded DNA binding
00003697molecular_functionsingle-stranded DNA binding
00003723molecular_functionRNA binding
00003779molecular_functionactin binding
00005515molecular_functionprotein binding
00005576cellular_componentextracellular region
00005634cellular_componentnucleus
00005737cellular_componentcytoplasm
00005739cellular_componentmitochondrion
00005829cellular_componentcytosol
00005856cellular_componentcytoskeleton
00005874cellular_componentmicrotubule
00005886cellular_componentplasma membrane
00006974biological_processDNA damage response
00007267biological_processcell-cell signaling
00007613biological_processmemory
00008017molecular_functionmicrotubule binding
00010288biological_processresponse to lead ion
00010506biological_processregulation of autophagy
00010629biological_processnegative regulation of gene expression
00010917biological_processnegative regulation of mitochondrial membrane potential
00015630cellular_componentmicrotubule cytoskeleton
00016020cellular_componentmembrane
00016072biological_processrRNA metabolic process
00017124molecular_functionSH3 domain binding
00019896biological_processaxonal transport of mitochondrion
00019899molecular_functionenzyme binding
00019901molecular_functionprotein kinase binding
00021954biological_processcentral nervous system neuron development
00030424cellular_componentaxon
00030425cellular_componentdendrite
00030426cellular_componentgrowth cone
00030673cellular_componentaxolemma
00030674molecular_functionprotein-macromolecule adaptor activity
00031110biological_processregulation of microtubule polymerization or depolymerization
00031113biological_processregulation of microtubule polymerization
00031116biological_processpositive regulation of microtubule polymerization
00031122biological_processcytoplasmic microtubule organization
00031175biological_processneuron projection development
00032930biological_processpositive regulation of superoxide anion generation
00033044biological_processregulation of chromosome organization
00034063biological_processstress granule assembly
00034185molecular_functionapolipoprotein binding
00034399cellular_componentnuclear periphery
00034452molecular_functiondynactin binding
00034605biological_processcellular response to heat
00034614biological_processcellular response to reactive oxygen species
00035091molecular_functionphosphatidylinositol binding
00036464cellular_componentcytoplasmic ribonucleoprotein granule
00036477cellular_componentsomatodendritic compartment
00042802molecular_functionidentical protein binding
00042995cellular_componentcell projection
00043005cellular_componentneuron projection
00043025cellular_componentneuronal cell body
00043197cellular_componentdendritic spine
00043565molecular_functionsequence-specific DNA binding
00044297cellular_componentcell body
00044304cellular_componentmain axon
00045121cellular_componentmembrane raft
00045298cellular_componenttubulin complex
00045773biological_processpositive regulation of axon extension
00046785biological_processmicrotubule polymerization
00048143biological_processastrocyte activation
00048167biological_processregulation of synaptic plasticity
00048312biological_processintracellular distribution of mitochondria
00048699biological_processgeneration of neurons
00050808biological_processsynapse organization
00050848biological_processregulation of calcium-mediated signaling
00051087molecular_functionprotein-folding chaperone binding
00051258biological_processprotein polymerization
00051721molecular_functionprotein phosphatase 2A binding
00051879molecular_functionHsp90 protein binding
00061564biological_processaxon development
00070507biological_processregulation of microtubule cytoskeleton organization
00071813molecular_functionlipoprotein particle binding
00072386biological_processplus-end-directed organelle transport along microtubule
00090140biological_processregulation of mitochondrial fission
00090258biological_processnegative regulation of mitochondrial fission
00097386cellular_componentglial cell projection
00097418cellular_componentneurofibrillary tangle
00097435biological_processsupramolecular fiber organization
00098930biological_processaxonal transport
00099077molecular_functionhistone-dependent DNA binding
00099609molecular_functionmicrotubule lateral binding
01900034biological_processregulation of cellular response to heat
01900452biological_processregulation of long-term synaptic depression
01902474biological_processpositive regulation of protein localization to synapse
01902936molecular_functionphosphatidylinositol bisphosphate binding
01902988biological_processneurofibrillary tangle assembly
01903748biological_processnegative regulation of establishment of protein localization to mitochondrion
01903829biological_processpositive regulation of protein localization
01904115cellular_componentaxon cytoplasm
01904428biological_processnegative regulation of tubulin deacetylation
01990000biological_processamyloid fibril formation
01990090biological_processcellular response to nerve growth factor stimulus
01990416biological_processcellular response to brain-derived neurotrophic factor stimulus
10000226biological_processmicrotubule cytoskeleton organization
10001774biological_processmicroglial cell activation
10003677molecular_functionDNA binding
10003680molecular_functionminor groove of adenine-thymine-rich DNA binding
10003690molecular_functiondouble-stranded DNA binding
10003697molecular_functionsingle-stranded DNA binding
10003723molecular_functionRNA binding
10003779molecular_functionactin binding
10005515molecular_functionprotein binding
10005576cellular_componentextracellular region
10005634cellular_componentnucleus
10005737cellular_componentcytoplasm
10005739cellular_componentmitochondrion
10005829cellular_componentcytosol
10005856cellular_componentcytoskeleton
10005874cellular_componentmicrotubule
10005886cellular_componentplasma membrane
10006974biological_processDNA damage response
10007267biological_processcell-cell signaling
10007613biological_processmemory
10008017molecular_functionmicrotubule binding
10010288biological_processresponse to lead ion
10010506biological_processregulation of autophagy
10010629biological_processnegative regulation of gene expression
10010917biological_processnegative regulation of mitochondrial membrane potential
10015630cellular_componentmicrotubule cytoskeleton
10016020cellular_componentmembrane
10016072biological_processrRNA metabolic process
10017124molecular_functionSH3 domain binding
10019896biological_processaxonal transport of mitochondrion
10019899molecular_functionenzyme binding
10019901molecular_functionprotein kinase binding
10021954biological_processcentral nervous system neuron development
10030424cellular_componentaxon
10030425cellular_componentdendrite
10030426cellular_componentgrowth cone
10030673cellular_componentaxolemma
10030674molecular_functionprotein-macromolecule adaptor activity
10031110biological_processregulation of microtubule polymerization or depolymerization
10031113biological_processregulation of microtubule polymerization
10031116biological_processpositive regulation of microtubule polymerization
10031122biological_processcytoplasmic microtubule organization
10031175biological_processneuron projection development
10032930biological_processpositive regulation of superoxide anion generation
10033044biological_processregulation of chromosome organization
10034063biological_processstress granule assembly
10034185molecular_functionapolipoprotein binding
10034399cellular_componentnuclear periphery
10034452molecular_functiondynactin binding
10034605biological_processcellular response to heat
10034614biological_processcellular response to reactive oxygen species
10035091molecular_functionphosphatidylinositol binding
10036464cellular_componentcytoplasmic ribonucleoprotein granule
10036477cellular_componentsomatodendritic compartment
10042802molecular_functionidentical protein binding
10042995cellular_componentcell projection
10043005cellular_componentneuron projection
10043025cellular_componentneuronal cell body
10043197cellular_componentdendritic spine
10043565molecular_functionsequence-specific DNA binding
10044297cellular_componentcell body
10044304cellular_componentmain axon
10045121cellular_componentmembrane raft
10045298cellular_componenttubulin complex
10045773biological_processpositive regulation of axon extension
10046785biological_processmicrotubule polymerization
10048143biological_processastrocyte activation
10048167biological_processregulation of synaptic plasticity
10048312biological_processintracellular distribution of mitochondria
10048699biological_processgeneration of neurons
10050808biological_processsynapse organization
10050848biological_processregulation of calcium-mediated signaling
10051087molecular_functionprotein-folding chaperone binding
10051258biological_processprotein polymerization
10051721molecular_functionprotein phosphatase 2A binding
10051879molecular_functionHsp90 protein binding
10061564biological_processaxon development
10070507biological_processregulation of microtubule cytoskeleton organization
10071813molecular_functionlipoprotein particle binding
10072386biological_processplus-end-directed organelle transport along microtubule
10090140biological_processregulation of mitochondrial fission
10090258biological_processnegative regulation of mitochondrial fission
10097386cellular_componentglial cell projection
10097418cellular_componentneurofibrillary tangle
10097435biological_processsupramolecular fiber organization
10098930biological_processaxonal transport
10099077molecular_functionhistone-dependent DNA binding
10099609molecular_functionmicrotubule lateral binding
11900034biological_processregulation of cellular response to heat
11900452biological_processregulation of long-term synaptic depression
11902474biological_processpositive regulation of protein localization to synapse
11902936molecular_functionphosphatidylinositol bisphosphate binding
11902988biological_processneurofibrillary tangle assembly
11903748biological_processnegative regulation of establishment of protein localization to mitochondrion
11903829biological_processpositive regulation of protein localization
11904115cellular_componentaxon cytoplasm
11904428biological_processnegative regulation of tubulin deacetylation
11990000biological_processamyloid fibril formation
11990090biological_processcellular response to nerve growth factor stimulus
11990416biological_processcellular response to brain-derived neurotrophic factor stimulus
A0000226biological_processmicrotubule cytoskeleton organization
A0001774biological_processmicroglial cell activation
A0003677molecular_functionDNA binding
A0003680molecular_functionminor groove of adenine-thymine-rich DNA binding
A0003690molecular_functiondouble-stranded DNA binding
A0003697molecular_functionsingle-stranded DNA binding
A0003723molecular_functionRNA binding
A0003779molecular_functionactin binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005874cellular_componentmicrotubule
A0005886cellular_componentplasma membrane
A0006974biological_processDNA damage response
A0007267biological_processcell-cell signaling
A0007613biological_processmemory
A0008017molecular_functionmicrotubule binding
A0010288biological_processresponse to lead ion
A0010506biological_processregulation of autophagy
A0010629biological_processnegative regulation of gene expression
A0010917biological_processnegative regulation of mitochondrial membrane potential
A0015630cellular_componentmicrotubule cytoskeleton
A0016020cellular_componentmembrane
A0016072biological_processrRNA metabolic process
A0017124molecular_functionSH3 domain binding
A0019896biological_processaxonal transport of mitochondrion
A0019899molecular_functionenzyme binding
A0019901molecular_functionprotein kinase binding
A0021954biological_processcentral nervous system neuron development
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0030426cellular_componentgrowth cone
A0030673cellular_componentaxolemma
A0030674molecular_functionprotein-macromolecule adaptor activity
A0031110biological_processregulation of microtubule polymerization or depolymerization
A0031113biological_processregulation of microtubule polymerization
A0031116biological_processpositive regulation of microtubule polymerization
A0031122biological_processcytoplasmic microtubule organization
A0031175biological_processneuron projection development
A0032930biological_processpositive regulation of superoxide anion generation
A0033044biological_processregulation of chromosome organization
A0034063biological_processstress granule assembly
A0034185molecular_functionapolipoprotein binding
A0034399cellular_componentnuclear periphery
A0034452molecular_functiondynactin binding
A0034605biological_processcellular response to heat
A0034614biological_processcellular response to reactive oxygen species
A0035091molecular_functionphosphatidylinositol binding
A0036464cellular_componentcytoplasmic ribonucleoprotein granule
A0036477cellular_componentsomatodendritic compartment
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043197cellular_componentdendritic spine
A0043565molecular_functionsequence-specific DNA binding
A0044297cellular_componentcell body
A0044304cellular_componentmain axon
A0045121cellular_componentmembrane raft
A0045298cellular_componenttubulin complex
A0045773biological_processpositive regulation of axon extension
A0046785biological_processmicrotubule polymerization
A0048143biological_processastrocyte activation
A0048167biological_processregulation of synaptic plasticity
A0048312biological_processintracellular distribution of mitochondria
A0048699biological_processgeneration of neurons
A0050808biological_processsynapse organization
A0050848biological_processregulation of calcium-mediated signaling
A0051087molecular_functionprotein-folding chaperone binding
A0051258biological_processprotein polymerization
A0051721molecular_functionprotein phosphatase 2A binding
A0051879molecular_functionHsp90 protein binding
A0061564biological_processaxon development
A0070507biological_processregulation of microtubule cytoskeleton organization
A0071813molecular_functionlipoprotein particle binding
A0072386biological_processplus-end-directed organelle transport along microtubule
A0090140biological_processregulation of mitochondrial fission
A0090258biological_processnegative regulation of mitochondrial fission
A0097386cellular_componentglial cell projection
A0097418cellular_componentneurofibrillary tangle
A0097435biological_processsupramolecular fiber organization
A0098930biological_processaxonal transport
A0099077molecular_functionhistone-dependent DNA binding
A0099609molecular_functionmicrotubule lateral binding
A1900034biological_processregulation of cellular response to heat
A1900452biological_processregulation of long-term synaptic depression
A1902474biological_processpositive regulation of protein localization to synapse
A1902936molecular_functionphosphatidylinositol bisphosphate binding
A1902988biological_processneurofibrillary tangle assembly
A1903748biological_processnegative regulation of establishment of protein localization to mitochondrion
A1903829biological_processpositive regulation of protein localization
A1904115cellular_componentaxon cytoplasm
A1904428biological_processnegative regulation of tubulin deacetylation
A1990000biological_processamyloid fibril formation
A1990090biological_processcellular response to nerve growth factor stimulus
A1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
B0000226biological_processmicrotubule cytoskeleton organization
B0001774biological_processmicroglial cell activation
B0003677molecular_functionDNA binding
B0003680molecular_functionminor groove of adenine-thymine-rich DNA binding
B0003690molecular_functiondouble-stranded DNA binding
B0003697molecular_functionsingle-stranded DNA binding
B0003723molecular_functionRNA binding
B0003779molecular_functionactin binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005874cellular_componentmicrotubule
B0005886cellular_componentplasma membrane
B0006974biological_processDNA damage response
B0007267biological_processcell-cell signaling
B0007613biological_processmemory
B0008017molecular_functionmicrotubule binding
B0010288biological_processresponse to lead ion
B0010506biological_processregulation of autophagy
B0010629biological_processnegative regulation of gene expression
B0010917biological_processnegative regulation of mitochondrial membrane potential
B0015630cellular_componentmicrotubule cytoskeleton
B0016020cellular_componentmembrane
B0016072biological_processrRNA metabolic process
B0017124molecular_functionSH3 domain binding
B0019896biological_processaxonal transport of mitochondrion
B0019899molecular_functionenzyme binding
B0019901molecular_functionprotein kinase binding
B0021954biological_processcentral nervous system neuron development
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0030426cellular_componentgrowth cone
B0030673cellular_componentaxolemma
B0030674molecular_functionprotein-macromolecule adaptor activity
B0031110biological_processregulation of microtubule polymerization or depolymerization
B0031113biological_processregulation of microtubule polymerization
B0031116biological_processpositive regulation of microtubule polymerization
B0031122biological_processcytoplasmic microtubule organization
B0031175biological_processneuron projection development
B0032930biological_processpositive regulation of superoxide anion generation
B0033044biological_processregulation of chromosome organization
B0034063biological_processstress granule assembly
B0034185molecular_functionapolipoprotein binding
B0034399cellular_componentnuclear periphery
B0034452molecular_functiondynactin binding
B0034605biological_processcellular response to heat
B0034614biological_processcellular response to reactive oxygen species
B0035091molecular_functionphosphatidylinositol binding
B0036464cellular_componentcytoplasmic ribonucleoprotein granule
B0036477cellular_componentsomatodendritic compartment
B0042802molecular_functionidentical protein binding
B0042995cellular_componentcell projection
B0043005cellular_componentneuron projection
B0043025cellular_componentneuronal cell body
B0043197cellular_componentdendritic spine
B0043565molecular_functionsequence-specific DNA binding
B0044297cellular_componentcell body
B0044304cellular_componentmain axon
B0045121cellular_componentmembrane raft
B0045298cellular_componenttubulin complex
B0045773biological_processpositive regulation of axon extension
B0046785biological_processmicrotubule polymerization
B0048143biological_processastrocyte activation
B0048167biological_processregulation of synaptic plasticity
B0048312biological_processintracellular distribution of mitochondria
B0048699biological_processgeneration of neurons
B0050808biological_processsynapse organization
B0050848biological_processregulation of calcium-mediated signaling
B0051087molecular_functionprotein-folding chaperone binding
B0051258biological_processprotein polymerization
B0051721molecular_functionprotein phosphatase 2A binding
B0051879molecular_functionHsp90 protein binding
B0061564biological_processaxon development
B0070507biological_processregulation of microtubule cytoskeleton organization
B0071813molecular_functionlipoprotein particle binding
B0072386biological_processplus-end-directed organelle transport along microtubule
B0090140biological_processregulation of mitochondrial fission
B0090258biological_processnegative regulation of mitochondrial fission
B0097386cellular_componentglial cell projection
B0097418cellular_componentneurofibrillary tangle
B0097435biological_processsupramolecular fiber organization
B0098930biological_processaxonal transport
B0099077molecular_functionhistone-dependent DNA binding
B0099609molecular_functionmicrotubule lateral binding
B1900034biological_processregulation of cellular response to heat
B1900452biological_processregulation of long-term synaptic depression
B1902474biological_processpositive regulation of protein localization to synapse
B1902936molecular_functionphosphatidylinositol bisphosphate binding
B1902988biological_processneurofibrillary tangle assembly
B1903748biological_processnegative regulation of establishment of protein localization to mitochondrion
B1903829biological_processpositive regulation of protein localization
B1904115cellular_componentaxon cytoplasm
B1904428biological_processnegative regulation of tubulin deacetylation
B1990000biological_processamyloid fibril formation
B1990090biological_processcellular response to nerve growth factor stimulus
B1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
C0000226biological_processmicrotubule cytoskeleton organization
C0001774biological_processmicroglial cell activation
C0003677molecular_functionDNA binding
C0003680molecular_functionminor groove of adenine-thymine-rich DNA binding
C0003690molecular_functiondouble-stranded DNA binding
C0003697molecular_functionsingle-stranded DNA binding
C0003723molecular_functionRNA binding
C0003779molecular_functionactin binding
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005874cellular_componentmicrotubule
C0005886cellular_componentplasma membrane
C0006974biological_processDNA damage response
C0007267biological_processcell-cell signaling
C0007613biological_processmemory
C0008017molecular_functionmicrotubule binding
C0010288biological_processresponse to lead ion
C0010506biological_processregulation of autophagy
C0010629biological_processnegative regulation of gene expression
C0010917biological_processnegative regulation of mitochondrial membrane potential
C0015630cellular_componentmicrotubule cytoskeleton
C0016020cellular_componentmembrane
C0016072biological_processrRNA metabolic process
C0017124molecular_functionSH3 domain binding
C0019896biological_processaxonal transport of mitochondrion
C0019899molecular_functionenzyme binding
C0019901molecular_functionprotein kinase binding
C0021954biological_processcentral nervous system neuron development
C0030424cellular_componentaxon
C0030425cellular_componentdendrite
C0030426cellular_componentgrowth cone
C0030673cellular_componentaxolemma
C0030674molecular_functionprotein-macromolecule adaptor activity
C0031110biological_processregulation of microtubule polymerization or depolymerization
C0031113biological_processregulation of microtubule polymerization
C0031116biological_processpositive regulation of microtubule polymerization
C0031122biological_processcytoplasmic microtubule organization
C0031175biological_processneuron projection development
C0032930biological_processpositive regulation of superoxide anion generation
C0033044biological_processregulation of chromosome organization
C0034063biological_processstress granule assembly
C0034185molecular_functionapolipoprotein binding
C0034399cellular_componentnuclear periphery
C0034452molecular_functiondynactin binding
C0034605biological_processcellular response to heat
C0034614biological_processcellular response to reactive oxygen species
C0035091molecular_functionphosphatidylinositol binding
C0036464cellular_componentcytoplasmic ribonucleoprotein granule
C0036477cellular_componentsomatodendritic compartment
C0042802molecular_functionidentical protein binding
C0042995cellular_componentcell projection
C0043005cellular_componentneuron projection
C0043025cellular_componentneuronal cell body
C0043197cellular_componentdendritic spine
C0043565molecular_functionsequence-specific DNA binding
C0044297cellular_componentcell body
C0044304cellular_componentmain axon
C0045121cellular_componentmembrane raft
C0045298cellular_componenttubulin complex
C0045773biological_processpositive regulation of axon extension
C0046785biological_processmicrotubule polymerization
C0048143biological_processastrocyte activation
C0048167biological_processregulation of synaptic plasticity
C0048312biological_processintracellular distribution of mitochondria
C0048699biological_processgeneration of neurons
C0050808biological_processsynapse organization
C0050848biological_processregulation of calcium-mediated signaling
C0051087molecular_functionprotein-folding chaperone binding
C0051258biological_processprotein polymerization
C0051721molecular_functionprotein phosphatase 2A binding
C0051879molecular_functionHsp90 protein binding
C0061564biological_processaxon development
C0070507biological_processregulation of microtubule cytoskeleton organization
C0071813molecular_functionlipoprotein particle binding
C0072386biological_processplus-end-directed organelle transport along microtubule
C0090140biological_processregulation of mitochondrial fission
C0090258biological_processnegative regulation of mitochondrial fission
C0097386cellular_componentglial cell projection
C0097418cellular_componentneurofibrillary tangle
C0097435biological_processsupramolecular fiber organization
C0098930biological_processaxonal transport
C0099077molecular_functionhistone-dependent DNA binding
C0099609molecular_functionmicrotubule lateral binding
C1900034biological_processregulation of cellular response to heat
C1900452biological_processregulation of long-term synaptic depression
C1902474biological_processpositive regulation of protein localization to synapse
C1902936molecular_functionphosphatidylinositol bisphosphate binding
C1902988biological_processneurofibrillary tangle assembly
C1903748biological_processnegative regulation of establishment of protein localization to mitochondrion
C1903829biological_processpositive regulation of protein localization
C1904115cellular_componentaxon cytoplasm
C1904428biological_processnegative regulation of tubulin deacetylation
C1990000biological_processamyloid fibril formation
C1990090biological_processcellular response to nerve growth factor stimulus
C1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
D0000226biological_processmicrotubule cytoskeleton organization
D0001774biological_processmicroglial cell activation
D0003677molecular_functionDNA binding
D0003680molecular_functionminor groove of adenine-thymine-rich DNA binding
D0003690molecular_functiondouble-stranded DNA binding
D0003697molecular_functionsingle-stranded DNA binding
D0003723molecular_functionRNA binding
D0003779molecular_functionactin binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005874cellular_componentmicrotubule
D0005886cellular_componentplasma membrane
D0006974biological_processDNA damage response
D0007267biological_processcell-cell signaling
D0007613biological_processmemory
D0008017molecular_functionmicrotubule binding
D0010288biological_processresponse to lead ion
D0010506biological_processregulation of autophagy
D0010629biological_processnegative regulation of gene expression
D0010917biological_processnegative regulation of mitochondrial membrane potential
D0015630cellular_componentmicrotubule cytoskeleton
D0016020cellular_componentmembrane
D0016072biological_processrRNA metabolic process
D0017124molecular_functionSH3 domain binding
D0019896biological_processaxonal transport of mitochondrion
D0019899molecular_functionenzyme binding
D0019901molecular_functionprotein kinase binding
D0021954biological_processcentral nervous system neuron development
D0030424cellular_componentaxon
D0030425cellular_componentdendrite
D0030426cellular_componentgrowth cone
D0030673cellular_componentaxolemma
D0030674molecular_functionprotein-macromolecule adaptor activity
D0031110biological_processregulation of microtubule polymerization or depolymerization
D0031113biological_processregulation of microtubule polymerization
D0031116biological_processpositive regulation of microtubule polymerization
D0031122biological_processcytoplasmic microtubule organization
D0031175biological_processneuron projection development
D0032930biological_processpositive regulation of superoxide anion generation
D0033044biological_processregulation of chromosome organization
D0034063biological_processstress granule assembly
D0034185molecular_functionapolipoprotein binding
D0034399cellular_componentnuclear periphery
D0034452molecular_functiondynactin binding
D0034605biological_processcellular response to heat
D0034614biological_processcellular response to reactive oxygen species
D0035091molecular_functionphosphatidylinositol binding
D0036464cellular_componentcytoplasmic ribonucleoprotein granule
D0036477cellular_componentsomatodendritic compartment
D0042802molecular_functionidentical protein binding
D0042995cellular_componentcell projection
D0043005cellular_componentneuron projection
D0043025cellular_componentneuronal cell body
D0043197cellular_componentdendritic spine
D0043565molecular_functionsequence-specific DNA binding
D0044297cellular_componentcell body
D0044304cellular_componentmain axon
D0045121cellular_componentmembrane raft
D0045298cellular_componenttubulin complex
D0045773biological_processpositive regulation of axon extension
D0046785biological_processmicrotubule polymerization
D0048143biological_processastrocyte activation
D0048167biological_processregulation of synaptic plasticity
D0048312biological_processintracellular distribution of mitochondria
D0048699biological_processgeneration of neurons
D0050808biological_processsynapse organization
D0050848biological_processregulation of calcium-mediated signaling
D0051087molecular_functionprotein-folding chaperone binding
D0051258biological_processprotein polymerization
D0051721molecular_functionprotein phosphatase 2A binding
D0051879molecular_functionHsp90 protein binding
D0061564biological_processaxon development
D0070507biological_processregulation of microtubule cytoskeleton organization
D0071813molecular_functionlipoprotein particle binding
D0072386biological_processplus-end-directed organelle transport along microtubule
D0090140biological_processregulation of mitochondrial fission
D0090258biological_processnegative regulation of mitochondrial fission
D0097386cellular_componentglial cell projection
D0097418cellular_componentneurofibrillary tangle
D0097435biological_processsupramolecular fiber organization
D0098930biological_processaxonal transport
D0099077molecular_functionhistone-dependent DNA binding
D0099609molecular_functionmicrotubule lateral binding
D1900034biological_processregulation of cellular response to heat
D1900452biological_processregulation of long-term synaptic depression
D1902474biological_processpositive regulation of protein localization to synapse
D1902936molecular_functionphosphatidylinositol bisphosphate binding
D1902988biological_processneurofibrillary tangle assembly
D1903748biological_processnegative regulation of establishment of protein localization to mitochondrion
D1903829biological_processpositive regulation of protein localization
D1904115cellular_componentaxon cytoplasm
D1904428biological_processnegative regulation of tubulin deacetylation
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Z1902474biological_processpositive regulation of protein localization to synapse
Z1902936molecular_functionphosphatidylinositol bisphosphate binding
Z1902988biological_processneurofibrillary tangle assembly
Z1903748biological_processnegative regulation of establishment of protein localization to mitochondrion
Z1903829biological_processpositive regulation of protein localization
Z1904115cellular_componentaxon cytoplasm
Z1904428biological_processnegative regulation of tubulin deacetylation
Z1990000biological_processamyloid fibril formation
Z1990090biological_processcellular response to nerve growth factor stimulus
Z1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
Functional Information from PROSITE/UniProt
site_idPS00229
Number of Residues13
DetailsTAU_MAP_1 Tau and MAP proteins tubulin-binding repeat signature. GSteNlkHqPGGG
ChainResidueDetails
AGLY261-GLY273
AGLY292-GLY304
AGLY323-GLY335
AGLY355-GLY367

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues372
DetailsSITE: Not glycated => ECO:0000269|PubMed:9326300
ChainResidueDetails
ALYS-293
ALYS-273
ALYS-250
ALYS64
ALYS74
ALYS75
ALYS77
ALYS148
ALYS180
ALYS190
ALYS224
ALYS240
ALYS254
ALYS257
ALYS267
ALYS274
ALYS290
ALYS294
ALYS298
ALYS311
ALYS317
ALYS321
ALYS331
ALYS340
ALYS343
ALYS370
ALYS375
ALYS383
ALYS385
ALYS395
ALYS438
BLYS-293
BLYS-273
BLYS-250
BLYS64
BLYS74
BLYS75
BLYS77
BLYS148
BLYS180
BLYS190
BLYS224
BLYS240
BLYS254
BLYS257
BLYS267
BLYS274
BLYS290
BLYS294
BLYS298
BLYS311
BLYS317
BLYS321
BLYS331
BLYS340
BLYS343
BLYS370
BLYS375
BLYS383
BLYS385
BLYS395
BLYS438
CLYS-293
CLYS-273
CLYS-250
CLYS64
CLYS74
CLYS75
CLYS77
CLYS148
CLYS180
CLYS190
CLYS224
CLYS240
CLYS254
CLYS257
CLYS267
CLYS274
CLYS290
CLYS294
CLYS298
CLYS311
CLYS317
CLYS321
CLYS331
CLYS340
CLYS343
CLYS370
CLYS375
CLYS383
CLYS385
CLYS395
CLYS438
DLYS-293
DLYS-273
DLYS-250
DLYS64
DLYS74
DLYS75
DLYS77
DLYS148
DLYS180
DLYS190
DLYS224
DLYS240
DLYS254
DLYS257
DLYS267
DLYS274
DLYS290
DLYS294
DLYS298
DLYS311
DLYS317
DLYS321
DLYS331
DLYS340
DLYS343
DLYS370
DLYS375
DLYS383
DLYS385
DLYS395
DLYS438
MLYS-293
MLYS-273
MLYS-250
MLYS64
MLYS74
MLYS75
MLYS77
MLYS148
MLYS180
MLYS190
MLYS224
MLYS240
MLYS254
MLYS257
MLYS267
MLYS274
MLYS290
MLYS294
MLYS298
MLYS311
MLYS317
MLYS321
MLYS331
MLYS340
MLYS343
MLYS370
MLYS375
MLYS383
MLYS385
MLYS395
MLYS438
NLYS-293
NLYS-273
NLYS-250
NLYS64
NLYS74
NLYS75
NLYS77
NLYS148
NLYS180
NLYS190
NLYS224
NLYS240
NLYS254
NLYS257
NLYS267
NLYS274
NLYS290
NLYS294
NLYS298
NLYS311
NLYS317
NLYS321
NLYS331
NLYS340
NLYS343
NLYS370
NLYS375
NLYS383
NLYS385
NLYS395
NLYS438
OLYS-293
OLYS-273
OLYS-250
OLYS64
OLYS74
OLYS75
OLYS77
OLYS148
OLYS180
OLYS190
OLYS224
OLYS240
OLYS254
OLYS257
OLYS267
OLYS274
OLYS290
OLYS294
OLYS298
OLYS311
OLYS317
OLYS321
OLYS331
OLYS340
OLYS343
OLYS370
OLYS375
OLYS383
OLYS385
OLYS395
OLYS438
PLYS-293
PLYS-273
PLYS-250
PLYS64
PLYS74
PLYS75
PLYS77
PLYS148
PLYS180
PLYS190
PLYS224
PLYS240
PLYS254
PLYS257
PLYS267
PLYS274
PLYS290
PLYS294
PLYS298
PLYS311
PLYS317
PLYS321
PLYS331
PLYS340
PLYS343
PLYS370
PLYS375
PLYS383
PLYS385
PLYS395
PLYS438
YLYS-293
YLYS-273
YLYS-250
YLYS64
YLYS74
YLYS75
YLYS77
YLYS148
YLYS180
YLYS190
YLYS224
YLYS240
YLYS254
YLYS257
YLYS267
YLYS274
YLYS290
YLYS294
YLYS298
YLYS311
YLYS317
YLYS321
YLYS331
YLYS340
YLYS343
YLYS370
YLYS375
YLYS383
YLYS385
YLYS395
YLYS438
ZLYS-293
ZLYS-273
ZLYS-250
ZLYS64
ZLYS74
ZLYS75
ZLYS77
ZLYS148
ZLYS180
ZLYS190
ZLYS224
ZLYS240
ZLYS254
ZLYS257
ZLYS267
ZLYS274
ZLYS290
ZLYS294
ZLYS298
ZLYS311
ZLYS317
ZLYS321
ZLYS331
ZLYS340
ZLYS343
ZLYS370
ZLYS375
ZLYS383
ZLYS385
ZLYS395
ZLYS438
0LYS-293
0LYS-273
0LYS-250
0LYS64
0LYS74
0LYS75
0LYS77
0LYS148
0LYS180
0LYS190
0LYS224
0LYS240
0LYS254
0LYS257
0LYS267
0LYS274
0LYS290
0LYS294
0LYS298
0LYS311
0LYS317
0LYS321
0LYS331
0LYS340
0LYS343
0LYS370
0LYS375
0LYS383
0LYS385
0LYS395
0LYS438
1LYS-293
1LYS-273
1LYS-250
1LYS64
1LYS74
1LYS75
1LYS77
1LYS148
1LYS180
1LYS190
1LYS224
1LYS240
1LYS254
1LYS257
1LYS267
1LYS274
1LYS290
1LYS294
1LYS298
1LYS311
1LYS317
1LYS321
1LYS331
1LYS340
1LYS343
1LYS370
1LYS375
1LYS383
1LYS385
1LYS395
1LYS438

site_idSWS_FT_FI2
Number of Residues12
DetailsMOD_RES: N-acetylalanine => ECO:0000269|PubMed:1512244
ChainResidueDetails
AALA-315
BALA-315
CALA-315
DALA-315
MALA-315
NALA-315
OALA-315
PALA-315
YALA-315
ZALA-315
0ALA-315
1ALA-315

site_idSWS_FT_FI3
Number of Residues12
DetailsMOD_RES: Phosphotyrosine; by FYN => ECO:0000269|PubMed:14999081
ChainResidueDetails
ATYR-299
BTYR-299
CTYR-299
DTYR-299
MTYR-299
NTYR-299
OTYR-299
PTYR-299
YTYR-299
ZTYR-299
0TYR-299
1TYR-299

site_idSWS_FT_FI4
Number of Residues24
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ATYR-288
ATYR394
BTYR-288
BTYR394
CTYR-288
CTYR394
DTYR-288
DTYR394
MTYR-288
MTYR394
NTYR-288
NTYR394
OTYR-288
OTYR394
PTYR-288
PTYR394
YTYR-288
YTYR394
ZTYR-288
ZTYR394
0TYR-288
0TYR394
1TYR-288
1TYR394

site_idSWS_FT_FI5
Number of Residues24
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P19332
ChainResidueDetails
ASER-271
ASER-256
BSER-271
BSER-256
CSER-271
CSER-256
DSER-271
DSER-256
MSER-271
MSER-256
NSER-271
NSER-256
OSER-271
OSER-256
PSER-271
PSER-256
YSER-271
YSER-256
ZSER-271
ZSER-256
0SER-271
0SER-256
1SER-271
1SER-256

site_idSWS_FT_FI6
Number of Residues60
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ATHR-248
ATHR-206
ATHR169
ATHR175
ATHR403
BTHR-248
BTHR-206
BTHR169
BTHR175
BTHR403
CTHR-248
CTHR-206
CTHR169
CTHR175
CTHR403
DTHR-248
DTHR-206
DTHR169
DTHR175
DTHR403
MTHR-248
MTHR-206
MTHR169
MTHR175
MTHR403
NTHR-248
NTHR-206
NTHR169
NTHR175
NTHR403
OTHR-248
OTHR-206
OTHR169
OTHR175
OTHR403
PTHR-248
PTHR-206
PTHR169
PTHR175
PTHR403
YTHR-248
YTHR-206
YTHR169
YTHR175
YTHR403
ZTHR-248
ZTHR-206
ZTHR169
ZTHR175
ZTHR403
0THR-248
0THR-206
0THR169
0THR175
0THR403
1THR-248
1THR-206
1THR169
1THR175
1THR403

site_idSWS_FT_FI7
Number of Residues12
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P19332
ChainResidueDetails
ATHR-246
BTHR-246
CTHR-246
DTHR-246
MTHR-246
NTHR-246
OTHR-246
PTHR-246
YTHR-246
ZTHR-246
0THR-246
1THR-246

site_idSWS_FT_FI8
Number of Residues12
DetailsMOD_RES: Phosphoserine; by SGK1 => ECO:0000269|PubMed:16982696
ChainResidueDetails
ASER-103
BSER-103
CSER-103
DSER-103
MSER-103
NSER-103
OSER-103
PSER-103
YSER-103
ZSER-103
0SER-103
1SER-103

site_idSWS_FT_FI9
Number of Residues12
DetailsMOD_RES: Phosphoserine; in PHF-tau => ECO:0000269|PubMed:1899488
ChainResidueDetails
ASER79
BSER79
CSER79
DSER79
MSER79
NSER79
OSER79
PSER79
YSER79
ZSER79
0SER79
1SER79

site_idSWS_FT_FI10
Number of Residues12
DetailsMOD_RES: Phosphothreonine; by PDPK1 => ECO:0000269|PubMed:9614189
ChainResidueDetails
ATHR153
BTHR153
CTHR153
DTHR153
MTHR153
NTHR153
OTHR153
PTHR153
YTHR153
ZTHR153
0THR153
1THR153

site_idSWS_FT_FI11
Number of Residues24
DetailsMOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
AARG155
AARG349
BARG155
BARG349
CARG155
CARG349
DARG155
DARG349
MARG155
MARG349
NARG155
NARG349
OARG155
OARG349
PARG155
PARG349
YARG155
YARG349
ZARG155
ZARG349
0ARG155
0ARG349
1ARG155
1ARG349

site_idSWS_FT_FI12
Number of Residues132
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ALYS163
ALYS281
ALYS298
ALYS311
ALYS317
ALYS321
ALYS331
ALYS343
ALYS347
ALYS369
ALYS385
BLYS163
BLYS281
BLYS298
BLYS311
BLYS317
BLYS321
BLYS331
BLYS343
BLYS347
BLYS369
BLYS385
CLYS163
CLYS281
CLYS298
CLYS311
CLYS317
CLYS321
CLYS331
CLYS343
CLYS347
CLYS369
CLYS385
DLYS163
DLYS281
DLYS298
DLYS311
DLYS317
DLYS321
DLYS331
DLYS343
DLYS347
DLYS369
DLYS385
MLYS163
MLYS281
MLYS298
MLYS311
MLYS317
MLYS321
MLYS331
MLYS343
MLYS347
MLYS369
MLYS385
NLYS163
NLYS281
NLYS298
NLYS311
NLYS317
NLYS321
NLYS331
NLYS343
NLYS347
NLYS369
NLYS385
OLYS163
OLYS281
OLYS298
OLYS311
OLYS317
OLYS321
OLYS331
OLYS343
OLYS347
OLYS369
OLYS385
PLYS163
PLYS281
PLYS298
PLYS311
PLYS317
PLYS321
PLYS331
PLYS343
PLYS347
PLYS369
PLYS385
YLYS163
YLYS281
YLYS298
YLYS311
YLYS317
YLYS321
YLYS331
YLYS343
YLYS347
YLYS369
YLYS385
ZLYS163
ZLYS281
ZLYS298
ZLYS311
ZLYS317
ZLYS321
ZLYS331
ZLYS343
ZLYS347
ZLYS369
ZLYS385
0LYS163
0LYS281
0LYS298
0LYS311
0LYS317
0LYS321
0LYS331
0LYS343
0LYS347
0LYS369
0LYS385
1LYS163
1LYS281
1LYS298
1LYS311
1LYS317
1LYS321
1LYS331
1LYS343
1LYS347
1LYS369
1LYS385

site_idSWS_FT_FI13
Number of Residues24
DetailsMOD_RES: Deamidated asparagine; in tau and PHF-tau; partial => ECO:0000269|PubMed:1512244
ChainResidueDetails
AASN167
AASN279
BASN167
BASN279
CASN167
CASN279
DASN167
DASN279
MASN167
MASN279
NASN167
NASN279
OASN167
OASN279
PASN167
PASN279
YASN167
YASN279
ZASN167
ZASN279
0ASN167
0ASN279
1ASN167
1ASN279

site_idSWS_FT_FI14
Number of Residues12
DetailsMOD_RES: Phosphothreonine; by PDPK1 => ECO:0000269|PubMed:15546861
ChainResidueDetails
ATHR181
BTHR181
CTHR181
DTHR181
MTHR181
NTHR181
OTHR181
PTHR181
YTHR181
ZTHR181
0THR181
1THR181

site_idSWS_FT_FI15
Number of Residues36
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ASER185
ASER191
ASER195
BSER185
BSER191
BSER195
CSER185
CSER191
CSER195
DSER185
DSER191
DSER195
MSER185
MSER191
MSER195
NSER185
NSER191
NSER195
OSER185
OSER191
OSER195
PSER185
PSER191
PSER195
YSER185
YSER191
YSER195
ZSER185
ZSER191
ZSER195
0SER185
0SER191
0SER195
1SER185
1SER191
1SER195

site_idSWS_FT_FI16
Number of Residues12
DetailsMOD_RES: Phosphotyrosine; by TTBK1 => ECO:0000269|PubMed:16923168
ChainResidueDetails
ATYR197
BTYR197
CTYR197
DTYR197
MTYR197
NTYR197
OTYR197
PTYR197
YTYR197
ZTYR197
0TYR197
1TYR197

site_idSWS_FT_FI17
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PDPK1 and TTBK1 => ECO:0000269|PubMed:16923168
ChainResidueDetails
ASER198
BSER198
CSER198
DSER198
MSER198
NSER198
OSER198
PSER198
YSER198
ZSER198
0SER198
1SER198

site_idSWS_FT_FI18
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PDPK1 and TTBK1 => ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16923168, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:9614189
ChainResidueDetails
ASER199
BSER199
CSER199
DSER199
MSER199
NSER199
OSER199
PSER199
YSER199
ZSER199
0SER199
1SER199

site_idSWS_FT_FI19
Number of Residues12
DetailsMOD_RES: Phosphoserine; by CK1, PDPK1 and TTBK1 => ECO:0000269|PubMed:14761950, ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16923168, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:21327254, ECO:0000269|PubMed:9614189, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER202
BSER202
CSER202
DSER202
MSER202
NSER202
OSER202
PSER202
YSER202
ZSER202
0SER202
1SER202

site_idSWS_FT_FI20
Number of Residues12
DetailsMOD_RES: Phosphothreonine; by CK1 and PDPK1 => ECO:0000269|PubMed:14761950, ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:19451179
ChainResidueDetails
ATHR205
BTHR205
CTHR205
DTHR205
MTHR205
NTHR205
OTHR205
PTHR205
YTHR205
ZTHR205
0THR205
1THR205

site_idSWS_FT_FI21
Number of Residues12
DetailsMOD_RES: Phosphothreonine; by BRSK1, BRSK2, DYRK2 and PDPK1 => ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:18599021, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:21985311, ECO:0000269|PubMed:9614189
ChainResidueDetails
ATHR212
BTHR212
CTHR212
DTHR212
MTHR212
NTHR212
OTHR212
PTHR212
YTHR212
ZTHR212
0THR212
1THR212

site_idSWS_FT_FI22
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:9614189
ChainResidueDetails
ASER214
BSER214
CSER214
DSER214
MSER214
NSER214
OSER214
PSER214
YSER214
ZSER214
0SER214
1SER214

site_idSWS_FT_FI23
Number of Residues12
DetailsMOD_RES: Phosphothreonine; by PDPK1 => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:19451179
ChainResidueDetails
ATHR217
BTHR217
CTHR217
DTHR217
MTHR217
NTHR217
OTHR217
PTHR217
YTHR217
ZTHR217
0THR217
1THR217

site_idSWS_FT_FI24
Number of Residues24
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ALYS225
ALYS290
BLYS225
BLYS290
CLYS225
CLYS290
DLYS225
DLYS290
MLYS225
MLYS290
NLYS225
NLYS290
OLYS225
OLYS290
PLYS225
PLYS290
YLYS225
YLYS290
ZLYS225
ZLYS290
0LYS225
0LYS290
1LYS225
1LYS290

site_idSWS_FT_FI25
Number of Residues12
DetailsMOD_RES: Phosphothreonine; by GSK3-beta and PDPK1 => ECO:0000269|PubMed:14690523, ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16443603, ECO:0007744|PubMed:23186163
ChainResidueDetails
ATHR231
BTHR231
CTHR231
DTHR231
MTHR231
NTHR231
OTHR231
PTHR231
YTHR231
ZTHR231
0THR231
1THR231

site_idSWS_FT_FI26
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PDPK1 => ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:9614189, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER235
BSER235
CSER235
DSER235
MSER235
NSER235
OSER235
PSER235
YSER235
ZSER235
0SER235
1SER235

site_idSWS_FT_FI27
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PHK => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:8999860
ChainResidueDetails
ASER237
BSER237
CSER237
DSER237
MSER237
NSER237
OSER237
PSER237
YSER237
ZSER237
0SER237
1SER237

site_idSWS_FT_FI28
Number of Residues12
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ALYS259
BLYS259
CLYS259
DLYS259
MLYS259
NLYS259
OLYS259
PLYS259
YLYS259
ZLYS259
0LYS259
1LYS259

site_idSWS_FT_FI29
Number of Residues12
DetailsMOD_RES: Phosphoserine; by MARK1, MARK2, MARK3, MARK4, BRSK1, BRSK2 and PHK => ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:21985311, ECO:0000269|PubMed:23666762, ECO:0000269|PubMed:7706316, ECO:0000269|PubMed:8999860, ECO:0000269|PubMed:9614189
ChainResidueDetails
ASER262
BSER262
CSER262
DSER262
MSER262
NSER262
OSER262
PSER262
YSER262
ZSER262
0SER262
1SER262

site_idSWS_FT_FI30
Number of Residues24
DetailsMOD_RES: Phosphoserine; by PHK => ECO:0000269|PubMed:8999860
ChainResidueDetails
ASER285
ASER352
BSER285
BSER352
CSER285
CSER352
DSER285
DSER352
MSER285
MSER352
NSER285
NSER352
OSER285
OSER352
PSER285
PSER352
YSER285
YSER352
ZSER285
ZSER352
0SER285
0SER352
1SER285
1SER352

site_idSWS_FT_FI31
Number of Residues36
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:7706316
ChainResidueDetails
ASER293
ASER324
ASER356
BSER293
BSER324
BSER356
CSER293
CSER324
CSER356
DSER293
DSER324
DSER356
MSER293
MSER324
MSER356
NSER293
NSER324
NSER356
OSER293
OSER324
OSER356
PSER293
PSER324
PSER356
YSER293
YSER324
YSER356
ZSER293
ZSER324
ZSER356
0SER293
0SER324
0SER356
1SER293
1SER324
1SER356

site_idSWS_FT_FI32
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PHK => ECO:0000269|PubMed:7706316, ECO:0000269|PubMed:8999860
ChainResidueDetails
ASER305
BSER305
CSER305
DSER305
MSER305
NSER305
OSER305
PSER305
YSER305
ZSER305
0SER305
1SER305

site_idSWS_FT_FI33
Number of Residues12
DetailsMOD_RES: Phosphoserine; by CK1 and PDPK1 => ECO:0000269|PubMed:14761950, ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:21327254, ECO:0000269|PubMed:9614189, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER396
BSER396
CSER396
DSER396
MSER396
NSER396
OSER396
PSER396
YSER396
ZSER396
0SER396
1SER396

site_idSWS_FT_FI34
Number of Residues12
DetailsMOD_RES: Phosphoserine; alternate => ECO:0007744|PubMed:19690332
ChainResidueDetails
ASER400
BSER400
CSER400
DSER400
MSER400
NSER400
OSER400
PSER400
YSER400
ZSER400
0SER400
1SER400

site_idSWS_FT_FI35
Number of Residues12
DetailsMOD_RES: Phosphoserine; by CK1 and PDPK1 => ECO:0000269|PubMed:14761950, ECO:0000269|PubMed:15546861, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:21327254, ECO:0000269|PubMed:9614189, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER404
BSER404
CSER404
DSER404
MSER404
NSER404
OSER404
PSER404
YSER404
ZSER404
0SER404
1SER404

site_idSWS_FT_FI36
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:15546861, ECO:0007744|PubMed:19690332
ChainResidueDetails
ASER409
BSER409
CSER409
DSER409
MSER409
NSER409
OSER409
PSER409
YSER409
ZSER409
0SER409
1SER409

site_idSWS_FT_FI37
Number of Residues12
DetailsMOD_RES: Phosphoserine; by CaMK2 and TTBK1 => ECO:0000269|PubMed:16923168
ChainResidueDetails
ASER416
BSER416
CSER416
DSER416
MSER416
NSER416
OSER416
PSER416
YSER416
ZSER416
0SER416
1SER416

site_idSWS_FT_FI38
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PDPK1 and TTBK1 => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16923168, ECO:0000269|PubMed:19451179, ECO:0000269|PubMed:9614189
ChainResidueDetails
ASER422
BSER422
CSER422
DSER422
MSER422
NSER422
OSER422
PSER422
YSER422
ZSER422
0SER422
1SER422

site_idSWS_FT_FI39
Number of Residues12
DetailsMOD_RES: Phosphothreonine; by TTBK1 => ECO:0000269|PubMed:16923168
ChainResidueDetails
ATHR427
BTHR427
CTHR427
DTHR427
MTHR427
NTHR427
OTHR427
PTHR427
YTHR427
ZTHR427
0THR427
1THR427

site_idSWS_FT_FI40
Number of Residues156
DetailsCARBOHYD: N-linked (Glc) (glycation) lysine; in PHF-tau; in vitro => ECO:0000269|PubMed:9326300
ChainResidueDetails
ALYS-230
ALYS66
ALYS150
ALYS163
ALYS174
ALYS225
ALYS234
ALYS259
ALYS280
ALYS281
ALYS347
ALYS353
ALYS369
BLYS-230
BLYS66
BLYS150
BLYS163
BLYS174
BLYS225
BLYS234
BLYS259
BLYS280
BLYS281
BLYS347
BLYS353
BLYS369
CLYS-230
CLYS66
CLYS150
CLYS163
CLYS174
CLYS225
CLYS234
CLYS259
CLYS280
CLYS281
CLYS347
CLYS353
CLYS369
DLYS-230
DLYS66
DLYS150
DLYS163
DLYS174
DLYS225
DLYS234
DLYS259
DLYS280
DLYS281
DLYS347
DLYS353
DLYS369
MLYS-230
MLYS66
MLYS150
MLYS163
MLYS174
MLYS225
MLYS234
MLYS259
MLYS280
MLYS281
MLYS347
MLYS353
MLYS369
NLYS-230
NLYS66
NLYS150
NLYS163
NLYS174
NLYS225
NLYS234
NLYS259
NLYS280
NLYS281
NLYS347
NLYS353
NLYS369
OLYS-230
OLYS66
OLYS150
OLYS163
OLYS174
OLYS225
OLYS234
OLYS259
OLYS280
OLYS281
OLYS347
OLYS353
OLYS369
PLYS-230
PLYS66
PLYS150
PLYS163
PLYS174
PLYS225
PLYS234
PLYS259
PLYS280
PLYS281
PLYS347
PLYS353
PLYS369
YLYS-230
YLYS66
YLYS150
YLYS163
YLYS174
YLYS225
YLYS234
YLYS259
YLYS280
YLYS281
YLYS347
YLYS353
YLYS369
ZLYS-230
ZLYS66
ZLYS150
ZLYS163
ZLYS174
ZLYS225
ZLYS234
ZLYS259
ZLYS280
ZLYS281
ZLYS347
ZLYS353
ZLYS369
0LYS-230
0LYS66
0LYS150
0LYS163
0LYS174
0LYS225
0LYS234
0LYS259
0LYS280
0LYS281
0LYS347
0LYS353
0LYS369
1LYS-230
1LYS66
1LYS150
1LYS163
1LYS174
1LYS225
1LYS234
1LYS259
1LYS280
1LYS281
1LYS347
1LYS353
1LYS369

site_idSWS_FT_FI41
Number of Residues24
DetailsCARBOHYD: O-linked (GlcNAc) serine => ECO:0000269|PubMed:21327254
ChainResidueDetails
ASER208
ASER238
BSER208
BSER238
CSER208
CSER238
DSER208
DSER238
MSER208
MSER238
NSER208
NSER238
OSER208
OSER238
PSER208
PSER238
YSER208
YSER238
ZSER208
ZSER238
0SER208
0SER238
1SER208
1SER238

site_idSWS_FT_FI42
Number of Residues12
DetailsCARBOHYD: O-linked (GlcNAc) serine; alternate => ECO:0000269|PubMed:21327254
ChainResidueDetails
ASER400
BSER400
CSER400
DSER400
MSER400
NSER400
OSER400
PSER400
YSER400
ZSER400
0SER400
1SER400

site_idSWS_FT_FI43
Number of Residues36
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ALYS-273
ALYS267
ALYS375
BLYS-273
BLYS267
BLYS375
CLYS-273
CLYS267
CLYS375
DLYS-273
DLYS267
DLYS375
MLYS-273
MLYS267
MLYS375
NLYS-273
NLYS267
NLYS375
OLYS-273
OLYS267
OLYS375
PLYS-273
PLYS267
PLYS375
YLYS-273
YLYS267
YLYS375
ZLYS-273
ZLYS267
ZLYS375
0LYS-273
0LYS267
0LYS375
1LYS-273
1LYS267
1LYS375

site_idSWS_FT_FI44
Number of Residues132
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P10637
ChainResidueDetails
ALYS259
ALYS281
ALYS298
ALYS317
ALYS321
ALYS331
ALYS343
ALYS347
ALYS369
ALYS385
BLYS259
BLYS281
BLYS298
BLYS317
BLYS321
BLYS331
BLYS343
BLYS347
BLYS369
BLYS385
CLYS259
CLYS281
CLYS298
CLYS317
CLYS321
CLYS331
CLYS343
CLYS347
CLYS369
CLYS385
DLYS259
DLYS281
DLYS298
DLYS317
DLYS321
DLYS331
DLYS343
DLYS347
DLYS369
DLYS385
MLYS259
MLYS281
MLYS298
MLYS317
MLYS321
MLYS331
MLYS343
MLYS347
MLYS369
MLYS385
NLYS259
NLYS281
NLYS298
NLYS317
NLYS321
NLYS331
NLYS343
NLYS347
NLYS369
NLYS385
OLYS259
OLYS281
OLYS298
OLYS317
OLYS321
OLYS331
OLYS343
OLYS347
OLYS369
OLYS385
PLYS259
PLYS281
PLYS298
PLYS317
PLYS321
PLYS331
PLYS343
PLYS347
PLYS369
PLYS385
YLYS259
YLYS281
YLYS298
YLYS317
YLYS321
YLYS331
YLYS343
YLYS347
YLYS369
YLYS385
ZLYS259
ZLYS281
ZLYS298
ZLYS317
ZLYS321
ZLYS331
ZLYS343
ZLYS347
ZLYS369
ZLYS385
0LYS259
0LYS281
0LYS298
0LYS317
0LYS321
0LYS331
0LYS343
0LYS347
0LYS369
0LYS385
1LYS259
1LYS281
1LYS298
1LYS317
1LYS321
1LYS331
1LYS343
1LYS347
1LYS369
1LYS385

site_idSWS_FT_FI45
Number of Residues36
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); in PHF-tau => ECO:0000269|PubMed:16443603
ChainResidueDetails
ALYS254
ALYS311
ALYS353
BLYS254
BLYS311
BLYS353
CLYS254
CLYS311
CLYS353
DLYS254
DLYS311
DLYS353
MLYS254
MLYS311
MLYS353
NLYS254
NLYS311
NLYS353
OLYS254
OLYS311
OLYS353
PLYS254
PLYS311
PLYS353
YLYS254
YLYS311
YLYS353
ZLYS254
ZLYS311
ZLYS353
0LYS254
0LYS311
0LYS353
1LYS254
1LYS311
1LYS353

237735

PDB entries from 2025-06-18

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