9B38

Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutamate receptor ionotropic, kainate 2	polymer	912	102976.6	4	UniProt (P42260) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	GluK2,Glutamate receptor 6,GluR-6,GluR6
2	E, H, J, L, O... (E, H, J, L, O...)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	6	In PDB GlyTouCan (G22768VO)
3	F, G, K, M, N... (F, G, K, M, N...)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	6	In PDB GlyTouCan (G15407YE)
4	I, P (I, P)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	AA, FA, NA, S (B, C, D, A)	GLUTAMIC ACID	non-polymer		147.1	4	Chemie (GLU)
6	BA, CA, DA, EA, GA... (B, C, D, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	18	Chemie (NAG)
7	IA, JA, V, W (C, A)	alpha-D-mannopyranose	non-polymer		180.2	4	Chemie (MAN)

Sequence modifications

A, B, C, D: 1 - 908 (UniProt: P42260)

PDB	External Database	Details
Val 567	Ile 567	conflict
Cys 571	Tyr 571	conflict
Leu 909	-	expression tag
Val 910	-	expression tag
Pro 911	-	expression tag
Arg 912	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	411906.3
Branched	Number of molecules	14
	Total formula weight	9833.0
Non-Polymers*	Number of molecules	26
	Total formula weight	5290.9
All*	Total formula weight	427030.2

*Water molecules are not included.