9B38
Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2752 |
| Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:8163463 |
| Chain | Residue | Details |
| A | THR32-PRO561 | |
| A | THR660-ASN819 | |
| B | THR32-PRO561 | |
| B | THR660-ASN819 | |
| C | THR32-PRO561 | |
| C | THR660-ASN819 | |
| D | THR32-PRO561 | |
| D | THR660-ASN819 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 240 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP562-ALA582 | |
| D | ASP562-ALA582 | |
| D | ILE639-LEU659 | |
| D | ILE820-GLY840 | |
| A | ILE639-LEU659 | |
| A | ILE820-GLY840 | |
| B | ASP562-ALA582 | |
| B | ILE639-LEU659 | |
| B | ILE820-GLY840 | |
| C | ASP562-ALA582 | |
| C | ILE639-LEU659 | |
| C | ILE820-GLY840 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 488 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:8163463 |
| Chain | Residue | Details |
| A | ARG583-GLY638 | |
| A | GLU841-ALA908 | |
| B | ARG583-GLY638 | |
| B | GLU841-ALA908 | |
| C | ARG583-GLY638 | |
| C | GLU841-ALA908 | |
| D | ARG583-GLY638 | |
| D | GLU841-ALA908 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15721240, ECO:0000269|PubMed:17115050, ECO:0007744|PDB:1S50, ECO:0007744|PDB:1S7Y, ECO:0007744|PDB:2I0B, ECO:0007744|PDB:2I0C |
| Chain | Residue | Details |
| A | PRO516 | |
| B | ALA689 | |
| B | THR690 | |
| B | GLU738 | |
| C | PRO516 | |
| C | ALA518 | |
| C | ARG523 | |
| C | ALA689 | |
| C | THR690 | |
| C | GLU738 | |
| D | PRO516 | |
| A | ALA518 | |
| D | ALA518 | |
| D | ARG523 | |
| D | ALA689 | |
| D | THR690 | |
| D | GLU738 | |
| A | ARG523 | |
| A | ALA689 | |
| A | THR690 | |
| A | GLU738 | |
| B | PRO516 | |
| B | ALA518 | |
| B | ARG523 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine; by PKC => ECO:0000250|UniProtKB:Q13002 |
| Chain | Residue | Details |
| A | SER846 | |
| A | SER868 | |
| B | SER846 | |
| B | SER868 | |
| C | SER846 | |
| C | SER868 | |
| D | SER846 | |
| D | SER868 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21791290 |
| Chain | Residue | Details |
| A | ASN67 | |
| D | ASN67 | |
| D | ASN378 | |
| D | ASN412 | |
| A | ASN378 | |
| A | ASN412 | |
| B | ASN67 | |
| B | ASN378 | |
| B | ASN412 | |
| C | ASN67 | |
| C | ASN378 | |
| C | ASN412 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 16 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN73 | |
| C | ASN275 | |
| C | ASN430 | |
| C | ASN546 | |
| D | ASN73 | |
| D | ASN275 | |
| D | ASN430 | |
| D | ASN546 | |
| A | ASN275 | |
| A | ASN430 | |
| A | ASN546 | |
| B | ASN73 | |
| B | ASN275 | |
| B | ASN430 | |
| B | ASN546 | |
| C | ASN73 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15677325 |
| Chain | Residue | Details |
| A | ASN423 | |
| B | ASN423 | |
| C | ASN423 | |
| D | ASN423 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15677325, ECO:0000269|PubMed:8163463 |
| Chain | Residue | Details |
| A | ASN751 | |
| B | ASN751 | |
| C | ASN751 | |
| D | ASN751 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000269|PubMed:17486098 |
| Chain | Residue | Details |
| A | LYS886 | |
| B | LYS886 | |
| C | LYS886 | |
| D | LYS886 |
