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9B33

Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one ConA dimer. Type II interface between GluK2 ligand-binding domain and ConA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(E, F)
Concanavalin Vpolymer23725622.42UniProt (C0HJY1)
Pfam (PF00139)
Canavalia ensiformis (jack bean)ConV
2C, E
(E, F)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, F
(E, F)
CALCIUM IONnon-polymer40.12Chemie (CA)
Sequence modifications
E, F: 1 - 237 (UniProt: C0HJY1)
PDBExternal DatabaseDetails
Asp 58Gly 58conflict
Ala 70Gly 70conflict
Met 129Val 129conflict
Glu 192Asp 192conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51244.8
Non-Polymers*Number of molecules4
Total formula weight211.0
All*Total formula weight51455.7
*Water molecules are not included.

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PDB entries from 2025-07-16

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