9B29
Cryo-EM structure of the mouse TRPM3 alpha 2 channel in complex with cholesteryl hemisuccinate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel, subfamily M, member 3 | polymer | 1739 | 198674.3 | 4 | UniProt (Q5F4S7) Pfam (PF18139) Pfam (PF00520) Pfam (PF16519) UniProt (by SIFTS) (J9SQF3) | Mus musculus (house mouse) | |
| 2 | E, J, O, T (A, B, C, D) | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | non-polymer | 718.0 | 4 | Chemie (6OU) | |||
| 3 | F, K, P, U (A, B, C, D) | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | non-polymer | 760.1 | 4 | Chemie (LBN) | |||
| 4 | G, H, L, M, Q... (A, B, C, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 8 | Chemie (Y01) | |||
| 5 | I, N, S, X (A, B, C, D) | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE | non-polymer | 535.7 | 4 | Chemie (PX2) |
Sequence modifications
A, B, C, D: 1 - 1709 (UniProt: Q5F4S7)
| PDB | External Database | Details |
|---|---|---|
| Ser 1710 | - | expression tag |
| Asn 1711 | - | expression tag |
| Ser 1712 | - | expression tag |
| Leu 1713 | - | expression tag |
| Glu 1714 | - | expression tag |
| Val 1715 | - | expression tag |
| Leu 1716 | - | expression tag |
| Phe 1717 | - | expression tag |
| Gln 1718 | - | expression tag |
| Gly 1719 | - | expression tag |
| Pro 1720 | - | expression tag |
| Asp 1721 | - | expression tag |
| Tyr 1722 | - | expression tag |
| Lys 1723 | - | expression tag |
| Asp 1724 | - | expression tag |
| Asp 1725 | - | expression tag |
| Asp 1726 | - | expression tag |
| Asp 1727 | - | expression tag |
| Lys 1728 | - | expression tag |
| Ala 1729 | - | expression tag |
| His 1730 | - | expression tag |
| His 1731 | - | expression tag |
| His 1732 | - | expression tag |
| His 1733 | - | expression tag |
| His 1734 | - | expression tag |
| His 1735 | - | expression tag |
| His 1736 | - | expression tag |
| His 1737 | - | expression tag |
| His 1738 | - | expression tag |
| His 1739 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 794697.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 11948.8 | |
| All* | Total formula weight | 806646.0 |
