9B13
Cryo-EM structure of phospholipase Cepsilon PH-COOH in complex with an antigen-binding fragment (composite structure)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 | polymer | 1469 | 165314.1 | 1 | UniProt (Q99P84) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF00788) | Rattus norvegicus (Norway rat) | Phosphoinositide phospholipase C-epsilon-1,Phospholipase C-epsilon-1,PLC-epsilon-1 |
| 2 | B (H) | Antigen-binding fragment heavy chain | polymer | 264 | 28234.5 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | Antigen-binding fragment light chain | polymer | 238 | 25794.9 | 1 | Homo sapiens (human) | ||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A: 837 - 2281 (UniProt: Q99P84)
| PDB | External Database | Details |
|---|---|---|
| Met 813 | - | initiating methionine |
| His 814 | - | expression tag |
| His 815 | - | expression tag |
| His 816 | - | expression tag |
| His 817 | - | expression tag |
| His 818 | - | expression tag |
| His 819 | - | expression tag |
| Ser 820 | - | expression tag |
| Ser 821 | - | expression tag |
| Gly 822 | - | expression tag |
| Val 823 | - | expression tag |
| Asp 824 | - | expression tag |
| Leu 825 | - | expression tag |
| Gly 826 | - | expression tag |
| Thr 827 | - | expression tag |
| Glu 828 | - | expression tag |
| Asn 829 | - | expression tag |
| Leu 830 | - | expression tag |
| Tyr 831 | - | expression tag |
| Phe 832 | - | expression tag |
| Gln 833 | - | expression tag |
| Ser 834 | - | expression tag |
| Asn 835 | - | expression tag |
| Ala 836 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 219343.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 219383.5 |
