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9B0Z

Structure of Optineurin bound to HOIP NZF1 domain and M1-linked diubiquitin, crystal form 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(B, A)
Optineurinpolymer9611017.52UniProt (Q96CV9)
Pfam (PF16516)
Homo sapiens (human)E3-14.7K-interacting protein,FIP-2,Huntingtin yeast partner L,Huntingtin-interacting protein 7,HIP-7,Huntingtin-interacting protein L,NEMO-related protein,Optic neuropathy-inducing protein,Transcription factor IIIA-interacting protein,TFIIIA-IntP
2B, F
(F, E)
E3 ubiquitin-protein ligase RNF31polymer303316.82UniProt (Q96EP0)Homo sapiens (human)HOIL-1-interacting protein,HOIP,RING finger protein 31,RING-type E3 ubiquitin transferase RNF31,Zinc in-between-RING-finger ubiquitin-associated domain protein
3C, D, G
(C, D, G)
Ubiquitinpolymer15217135.73UniProt (P0CG47)
Pfam (PF00240)
Homo sapiens (human)
4H, I
(F, E)
ZINC IONnon-polymer65.42Chemie (ZN)
5J, K, L, M
(B, C, D, A)
waterwater18.045Chemie (HOH)
Sequence modifications
B, A: 419 - 512 (UniProt: Q96CV9)
PDBExternal DatabaseDetails
Gly 417-expression tag
Pro 418-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight80075.6
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight80206.4
*Water molecules are not included.

243531

PDB entries from 2025-10-22

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