9B0B
Structure of Optineurin bound to HOIP NZF1 domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E (A, B, C, D) | Optineurin | polymer | 96 | 11043.5 | 4 | UniProt (Q96CV9) Pfam (PF16516) | Homo sapiens (human) | E3-14.7K-interacting protein,FIP-2,Huntingtin yeast partner L,Huntingtin-interacting protein 7,HIP-7,Huntingtin-interacting protein L,NEMO-related protein,Optic neuropathy-inducing protein,Transcription factor IIIA-interacting protein,TFIIIA-IntP |
| 2 | C, F (G, E) | E3 ubiquitin-protein ligase RNF31 | polymer | 30 | 3316.8 | 2 | UniProt (Q96EP0) | Homo sapiens (human) | HOIL-1-interacting protein,HOIP,RING finger protein 31,RING-type E3 ubiquitin transferase RNF31,Zinc in-between-RING-finger ubiquitin-associated domain protein |
| 3 | G, H, J, K, M... (A, B, G, C, D...) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 10 | Chemie (PGE) | |||
| 4 | I, N (B, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | L, S (G, E) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | U, V, W, X, Y... (A, B, G, C, D...) | water | water | 18.0 | 283 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 419 - 512 (UniProt: Q96CV9)
| PDB | External Database | Details |
|---|---|---|
| Gly 417 | - | expression tag |
| Pro 418 | - | expression tag |
| Ser 472 | Cys 472 | engineered mutation |
| Glu 473 | Ser 473 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 50807.5 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2021.0 | |
| All* | Total formula weight | 52828.5 |
