9AY9
Co-crystal structure of human PRMT9 in complex with MRK-990 inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein arginine N-methyltransferase 9 | polymer | 720 | 80486.3 | 4 | UniProt (Q6P2P2) Pfam (PF06325) Pfam (PF22528) | Homo sapiens (human) | Protein arginine N-methyltransferase 10 |
| 2 | E, F, G, I (A, B, C, D) | 7-[5-S-(4-{[(2-tert-butylpyridin-3-yl)methyl]amino}butyl)-5-thio-beta-D-ribofuranosyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 514.7 | 4 | Chemie (A1AHM) | |||
| 3 | H, J (C, D) | UNKNOWN ATOM OR ION | non-polymer | 2 | Chemie (UNX) | ||||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 598 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 127 - 845 (UniProt: Q6P2P2)
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 321945.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2058.7 | |
| All* | Total formula weight | 324003.9 |
