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9AVR

Human eIF4A-1 in complex with AMP-PNP, RNA, and the inhibitor silvestrol

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Eukaryotic initiation factor 4A-Ipolymer40646207.81UniProt (P60842)
Pfam (PF00270)
Pfam (PF00271)
Homo sapiens (human)eIF-4A-I,eIF4A-I,ATP-dependent RNA helicase eIF4A-1
2B
(B)
RNA oligonucleotide (AG)5polymer103327.11Homo sapiens
3C
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E, F
(A)
IODIDE IONnon-polymer126.92Chemie (IOD)
6G
(B)
silvestrolnon-polymer654.71Chemie (A1AG8)
7H, I
(A, B)
waterwater18.0316Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight49534.9
Non-Polymers*Number of molecules5
Total formula weight1439.0
All*Total formula weight50973.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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