9ATU
Bifunctional Inhibition of Neutrophil Elastase by Eap4 from S. aureus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D, E (A, C, D, F) | Neutrophil elastase | polymer | 218 | 23319.0 | 4 | UniProt (P08246) Pfam (PF00089) | Homo sapiens (human) | Bone marrow serine protease,Elastase-2,Human leukocyte elastase,HLE,Medullasin,PMN elastase |
| 2 | B, F (B, E) | Extracellular Adherence Protein | polymer | 108 | 12336.5 | 2 | UniProt (Q99QS1) Pfam (PF03642) | Staphylococcus aureus subsp. aureus Mu50 | Protein map |
| 3 | G, J, L, M, N (G, J, L, M, N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 5 | In PDB GlyTouCan (G32152BH) | |||
| 4 | H, I (H, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 5 | K (K) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | O, P, Q, R, S... (A, B, C, D, F...) | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
B, E: 372 - 476 (UniProt: Q99QS1)
| PDB | External Database | Details |
|---|---|---|
| Gly 369 | - | expression tag |
| Ser 370 | - | expression tag |
| Thr 371 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 117948.9 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 5391.0 | |
| All* | Total formula weight | 123339.9 |
