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8ZND

Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH and a substrate in the steady stage of reaction

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutamate dehydrogenasepolymer41646360.01UniProt (O74024)Thermococcus profundusGDH
2B
(A)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
3C
(A)
waterwater18.024Chemie (HOH)
Sequence modifications
A: 4 - 419 (UniProt: O74024)
PDBExternal DatabaseDetails
Phe 89Trp 89engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight46360.0
Non-Polymers*Number of molecules1
Total formula weight745.4
All*Total formula weight47105.4
*Water molecules are not included.

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PDB entries from 2026-01-21

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