8ZMS
Acetylcholine-bound VAChT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 | polymer | 1047 | 112705.2 | 1 | UniProt (P0AEX9) UniProt (Q16572) Pfam (PF01547) Pfam (PF07690) | Escherichia coli (strain K12) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,VAChT,Solute carrier family 18 member 3 |
| 2 | B (A) | ACETYLCHOLINE | non-polymer | 146.2 | 1 | Chemie (ACH) |
Sequence modifications
A: -343 - 19 (UniProt: P0AEX9)
A: 34 - 524 (UniProt: Q16572)
A: 535 - 702 (PDB: 8ZMS)
| PDB | External Database | Details |
|---|---|---|
| Met -344 | - | initiating methionine |
| Ile -150 | Val 222 | conflict |
| Val -34 | Ala 338 | conflict |
| Val -29 | Ile 343 | conflict |
| Ala 13 | Glu 385 | conflict |
| Ala 16 | Lys 388 | conflict |
| Ala 17 | Asp 389 | conflict |
| Ala 20 | - | linker |
| Glu 21 | - | linker |
| Glu 22 | - | linker |
| Glu 23 | - | linker |
| Lys 24 | - | linker |
| Arg 25 | - | linker |
| Lys 26 | - | linker |
| Ala 27 | - | linker |
| Glu 28 | - | linker |
| Glu 29 | - | linker |
| Glu 30 | - | linker |
| Lys 31 | - | linker |
| Arg 32 | - | linker |
| Lys 33 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 520 | Ala 520 | engineered mutation |
| Gly 525 | - | linker |
| Gly 526 | - | linker |
| Gly 527 | - | linker |
| Gly 528 | - | linker |
| Ser 529 | - | linker |
| Gly 530 | - | linker |
| Gly 531 | - | linker |
| Gly 532 | - | linker |
| Gly 533 | - | linker |
| Ser 534 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 112705.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 146.2 | |
| All* | Total formula weight | 112851.4 |
