8ZMS

Acetylcholine-bound VAChT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005277	molecular_function	acetylcholine transmembrane transporter activity
A	0005278	molecular_function	acetylcholine:proton antiporter activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006836	biological_process	neurotransmitter transport
A	0006974	biological_process	DNA damage response
A	0007268	biological_process	chemical synaptic transmission
A	0008643	biological_process	carbohydrate transport
A	0014057	biological_process	positive regulation of acetylcholine secretion, neurotransmission
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015311	molecular_function	monoamine:proton antiporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0030121	cellular_component	AP-1 adaptor complex
A	0030122	cellular_component	AP-2 adaptor complex
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0030669	cellular_component	clathrin-coated endocytic vesicle membrane
A	0030672	cellular_component	synaptic vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0043195	cellular_component	terminal bouton
A	0051610	biological_process	serotonin uptake
A	0051630	biological_process	acetylcholine uptake
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060201	cellular_component	clathrin-sculpted acetylcholine transport vesicle membrane
A	0060326	biological_process	cell chemotaxis
A	1900273	biological_process	positive regulation of long-term synaptic potentiation
A	1901982	molecular_function	maltose binding
A	1902600	biological_process	proton transmembrane transport
A	1904398	biological_process	positive regulation of neuromuscular junction development
A	1990060	cellular_component	maltose transport complex

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO-239-ASN-222

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	35
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	42
Details	Topological domain: {"description":"Lumenal, vesicle","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Important for transporter activity","evidences":[{"source":"UniProtKB","id":"Q62666","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Site: {"description":"Important for transporter activity","evidences":[{"source":"PubMed","id":"20225888","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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