8ZHF

SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, head-to-head aggregate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, J, K... (A, B, C, D, E...)	Spike glycoprotein,Fibritin,Expression Tag	polymer	1278	141253.9	6	UniProt (P0DTC2) UniProt (A0A346FJN8) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	S glycoprotein,E2,Peplomer protein,Phage neck whiskers protein
2	D, F, H, M, O... (H, F, J, R, M...)	Heavy chain of R1-26 Fab	polymer	243	25908.3	6		Homo sapiens (human)
3	E, G, I, N, P... (L, G, K, U, N...)	Light chain of R1-26 Fab	polymer	240	25558.2	6		Homo sapiens (human)
4	AA, BA, CA, DA, EA... (a, b, c, d, e...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	30	In PDB GlyTouCan (G42666HT)
5	AB, AC, AD, BB, BC... (A, D, I, B, E...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	60	Chemie (NAG)

Sequence modifications

A, B, C, D, E, I: 11 - 1208 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 682	Arg 682	conflict
Ser 683	Arg 683	conflict
Ser 685	Arg 685	conflict
Pro 817	Phe 817	conflict
Pro 892	Ala 892	conflict
Pro 899	Ala 899	conflict
Pro 942	Ala 942	conflict
Pro 986	Lys 986	variant
Pro 987	Val 987	variant
Gly 1209	-	linker
Ser 1210	-	linker

A, B, C, D, E, I: 1211 - 1237 (UniProt: A0A346FJN8)
A, B, C, D, E, I: 1238 - 1288 (PDB: 8ZHF)

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	1156322.5
Branched	Number of molecules	30
	Total formula weight	12732.0
Non-Polymers*	Number of molecules	60
	Total formula weight	13272.5
All*	Total formula weight	1182327.0

*Water molecules are not included.