8ZHF
SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, head-to-head aggregate
Functional Information from PROSITE/UniProt
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH |
Chain | Residue | Details |
L | TYR202-HIS208 | |
H | TYR201-HIS207 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
Chain | Residue | Details |
A | SER685 | |
B | SER685 | |
C | SER685 | |
D | SER685 | |
E | SER685 | |
I | SER685 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
Chain | Residue | Details |
A | ARG815 | |
B | ARG815 | |
C | ARG815 | |
D | ARG815 | |
E | ARG815 | |
I | ARG815 |
site_id | SWS_FT_FI3 |
Number of Residues | 18 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN17 | |
D | ASN17 | |
D | ASN1158 | |
D | ASN1173 | |
E | ASN17 | |
E | ASN1158 | |
E | ASN1173 | |
I | ASN17 | |
I | ASN1158 | |
I | ASN1173 | |
A | ASN1158 | |
A | ASN1173 | |
B | ASN17 | |
B | ASN1158 | |
B | ASN1173 | |
C | ASN17 | |
C | ASN1158 | |
C | ASN1173 |
site_id | SWS_FT_FI4 |
Number of Residues | 30 |
Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN61 | |
B | ASN1074 | |
C | ASN61 | |
C | ASN122 | |
C | ASN717 | |
C | ASN801 | |
C | ASN1074 | |
D | ASN61 | |
D | ASN122 | |
D | ASN717 | |
D | ASN801 | |
A | ASN122 | |
D | ASN1074 | |
E | ASN61 | |
E | ASN122 | |
E | ASN717 | |
E | ASN801 | |
E | ASN1074 | |
I | ASN61 | |
I | ASN122 | |
I | ASN717 | |
I | ASN801 | |
A | ASN717 | |
I | ASN1074 | |
A | ASN801 | |
A | ASN1074 | |
B | ASN61 | |
B | ASN122 | |
B | ASN717 | |
B | ASN801 |
site_id | SWS_FT_FI5 |
Number of Residues | 18 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN74 | |
D | ASN74 | |
D | ASN149 | |
D | ASN1194 | |
E | ASN74 | |
E | ASN149 | |
E | ASN1194 | |
I | ASN74 | |
I | ASN149 | |
I | ASN1194 | |
A | ASN149 | |
A | ASN1194 | |
B | ASN74 | |
B | ASN149 | |
B | ASN1194 | |
C | ASN74 | |
C | ASN149 | |
C | ASN1194 |
site_id | SWS_FT_FI6 |
Number of Residues | 42 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN165 | |
B | ASN331 | |
B | ASN343 | |
B | ASN616 | |
B | ASN657 | |
B | ASN1098 | |
C | ASN165 | |
C | ASN282 | |
C | ASN331 | |
C | ASN343 | |
C | ASN616 | |
A | ASN282 | |
C | ASN657 | |
C | ASN1098 | |
D | ASN165 | |
D | ASN282 | |
D | ASN331 | |
D | ASN343 | |
D | ASN616 | |
D | ASN657 | |
D | ASN1098 | |
E | ASN165 | |
A | ASN331 | |
E | ASN282 | |
E | ASN331 | |
E | ASN343 | |
E | ASN616 | |
E | ASN657 | |
E | ASN1098 | |
I | ASN165 | |
I | ASN282 | |
I | ASN331 | |
I | ASN343 | |
A | ASN343 | |
I | ASN616 | |
I | ASN657 | |
I | ASN1098 | |
A | ASN616 | |
A | ASN657 | |
A | ASN1098 | |
B | ASN165 | |
B | ASN282 |
site_id | SWS_FT_FI7 |
Number of Residues | 12 |
Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN234 | |
E | ASN709 | |
I | ASN234 | |
I | ASN709 | |
A | ASN709 | |
B | ASN234 | |
B | ASN709 | |
C | ASN234 | |
C | ASN709 | |
D | ASN234 | |
D | ASN709 | |
E | ASN234 |
site_id | SWS_FT_FI8 |
Number of Residues | 6 |
Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
Chain | Residue | Details |
A | THR323 | |
B | THR323 | |
C | THR323 | |
D | THR323 | |
E | THR323 | |
I | THR323 |
site_id | SWS_FT_FI9 |
Number of Residues | 6 |
Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
Chain | Residue | Details |
A | SER325 | |
B | SER325 | |
C | SER325 | |
D | SER325 | |
E | SER325 | |
I | SER325 |
site_id | SWS_FT_FI10 |
Number of Residues | 6 |
Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN603 | |
B | ASN603 | |
C | ASN603 | |
D | ASN603 | |
E | ASN603 | |
I | ASN603 |
site_id | SWS_FT_FI11 |
Number of Residues | 12 |
Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
Chain | Residue | Details |
A | THR676 | |
E | THR678 | |
I | THR676 | |
I | THR678 | |
A | THR678 | |
B | THR676 | |
B | THR678 | |
C | THR676 | |
C | THR678 | |
D | THR676 | |
D | THR678 | |
E | THR676 |
site_id | SWS_FT_FI12 |
Number of Residues | 6 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN1134 | |
B | ASN1134 | |
C | ASN1134 | |
D | ASN1134 | |
E | ASN1134 | |
I | ASN1134 |