8ZEM
Crystal Structure of NLRP3 NACHT domain in complex with NP3-1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NACHT, LRR and PYD domains-containing protein 3 | polymer | 551 | 64243.4 | 1 | UniProt (Q96P20) Pfam (PF14484) Pfam (PF05729) Pfam (PF17779) Pfam (PF17776) | Homo sapiens (human) | Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1 |
| 2 | B (A) | 1-[5-[2,3-bis(chloranyl)phenyl]-2,3-dihydro-1~{H}-inden-4-yl]-3-[4-(2-oxidanylpropan-2-yl)thiophen-2-yl]sulfonyl-urea | non-polymer | 525.5 | 1 | Chemie (A1D79) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
A: 131 - 679 (UniProt: Q96P20)
| PDB | External Database | Details |
|---|---|---|
| Ser 129 | - | expression tag |
| Gly 130 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 64243.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 952.7 | |
| All* | Total formula weight | 65196.1 |
