8ZBH
Crystal structure of TEAD3 YAP binding domain with compound 3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Transcriptional enhancer factor TEF-5 | polymer | 221 | 25395.9 | 3 | UniProt (Q99594) Pfam (PF17725) | Homo sapiens (human) | DTEF-1,TEA domain family member 3,TEAD-3 |
| 2 | D, E, F (A, B, C) | 1-[7-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-one | non-polymer | 333.3 | 3 | Chemie (A1L1O) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B, C: 216 - 435 (UniProt: Q99594)
| PDB | External Database | Details |
|---|---|---|
| Ser 215 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 76187.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1000.0 | |
| All* | Total formula weight | 77187.6 |
