8ZBH

Crystal structure of TEAD3 YAP binding domain with compound 3

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	PAL/PLS BEAMLINE 5C (4A)
Synchrotron site	PAL/PLS
Beamline	5C (4A)
Temperature [K]	100
Detector technology	CCD
Collection date	2022-05-03
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.97
Spacegroup name	P 21 21 21
Unit cell lengths	46.170, 101.740, 149.080
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	28.170 - 2.600
R-factor	0.2148
Rwork	0.212
R-free	0.27020
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.010
RMSD bond angle	1.334
Data reduction software	XDS
Data scaling software	XDS
Phasing software	ELVES
Refinement software	PHENIX (1.20.1_4487)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	28.170	2.693
High resolution limit [Å]	2.600	2.600
Rmerge	0.035	0.358
Number of reflections	22344	2194
<I/σ(I)>	15.12	2.07
Completeness [%]	99.8
Redundancy	2
CC(1/2)	0.999	0.806

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		300	0.1M HEPES pH 7.5, 0.2M Ammonium acetate, 18% PEG 3350