8Z5T

human phosphorylase kinase - phosphorylation and Ca2+ bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I, M (A, E, I, M)	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform	polymer	1223	140108.7	4	UniProt (P46020) Pfam (PF00723) Pfam (PF19292)	Homo sapiens (human)	Phosphorylase kinase alpha M subunit
2	B, F, J, N (B, F, J, N)	Phosphorylase b kinase regulatory subunit beta	polymer	1093	126152.7	4	UniProt (Q93100) Pfam (PF00723) Pfam (PF19292)	Homo sapiens (human)	Phosphorylase kinase subunit beta
3	C, G, K, O (C, G, K, O)	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	polymer	387	45084.7	4	UniProt (Q16816) Pfam (PF00069)	Homo sapiens (human)	PHK-gamma-M,Phosphorylase kinase subunit gamma-1,Serine/threonine-protein kinase PHKG1
4	D, H, L, P (D, H, L, P)	Calmodulin-3	polymer	168	18921.6	4	UniProt (P0DP25) Pfam (PF13499)	Homo sapiens (human)
5	Q, R, S, T, U... (B, C, F, G, J...)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	8	Chemie (ATP)

Sequence modifications

D, H, L, P: 1 - 149 (UniProt: P0DP25)

PDB	External Database	Details
Asp -18	-	expression tag
Tyr -17	-	expression tag
Lys -16	-	expression tag
Asp -15	-	expression tag
Asp -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Lys -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Pro -8	-	expression tag
Asp -7	-	expression tag
Glu -6	-	expression tag
Val -5	-	expression tag
Asp -4	-	expression tag
Ala -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	1321070.4
Non-Polymers*	Number of molecules	8
	Total formula weight	4057.4
All*	Total formula weight	1325127.9

*Water molecules are not included.