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8Z39

Crystal structure of Sonic hedgehog in complex with antibody 5E1 mutant L-T56A with metals

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sonic hedgehog protein N-productpolymer16919122.51UniProt (Q15465)
Pfam (PF01085)
Homo sapiens (human)ShhN,Shh N-terminal processed signaling domains,ShhNp
2B
(H)
Heavy chain of antibody 5E1polymer24126318.31Homo sapiens
3C
(L)
Light chain of antibody 5E1polymer23626035.81Homo sapiens
4D, E
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
5F
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
6G
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
7H
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
8I, J, K
(A, H, L)
waterwater18.0625Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight71476.6
Non-Polymers*Number of molecules5
Total formula weight277.1
All*Total formula weight71753.6
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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