8Z39
Crystal structure of Sonic hedgehog in complex with antibody 5E1 mutant L-T56A with metals
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR192-HIS198 | |
| H | TYR200-HIS206 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20504762, ECO:0007744|PDB:3MXW |
| Chain | Residue | Details |
| A | GLU89 | |
| A | GLU90 | |
| A | ASP95 | |
| A | THR125 | |
| A | GLU126 | |
| A | ASP129 | |
| A | ASP131 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10753901, ECO:0000269|PubMed:20504762, ECO:0007744|PDB:3M1N, ECO:0007744|PDB:3MXW |
| Chain | Residue | Details |
| A | HIS140 | |
| A | ASP147 | |
| A | HIS182 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000250|UniProtKB:Q02936 |
| Chain | Residue | Details |
| A | GLY197 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | LIPID: Cholesterol glycine ester => ECO:0000250|UniProtKB:Q62226 |
| Chain | Residue | Details |
| A | GLY197 |
