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8Z37

Crystal structure of human STING ligand binding domain.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Stimulator of interferon genes proteinpolymer19222012.71UniProt (Q86WV6)
Pfam (PF15009)
Homo sapiens (human)hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173
2B
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
3C
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
4D
(A)
(1P)-3',5-di(prop-2-en-1-yl)[1,1'-biphenyl]-2,4'-diolnon-polymer266.31Chemie (Y4T)
5E
(A)
waterwater18.030Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22012.7
Non-Polymers*Number of molecules3
Total formula weight341.9
All*Total formula weight22354.6
*Water molecules are not included.

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PDB entries from 2025-12-17

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