8Z2V
Crystal structure of Sonic hedgehog in complex with antibody 5E1 mutant H-R102A with metals
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sonic hedgehog protein N-product | polymer | 169 | 19122.5 | 1 | UniProt (Q15465) Pfam (PF01085) | Homo sapiens (human) | ShhN,Shh N-terminal processed signaling domains,ShhNp |
| 2 | B (H) | Heavy chain of antibody 5E1 | polymer | 241 | 26232.1 | 1 | Homo sapiens | ||
| 3 | C (L) | Light chain of antibody 5E1 | polymer | 235 | 26008.8 | 1 | Homo sapiens | ||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F, G (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | H (H) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | I, J, K (A, H, L) | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71363.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 273.1 | |
| All* | Total formula weight | 71636.5 |
