8Z22

Crystal structure of the liprin-alpha2/RIM1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Regulating synaptic membrane exocytosis 1	polymer	175	19229.3	2	UniProt (A0A8I6GEN0)	Rattus norvegicus (Rat)
2	C, D (C, D)	Liprin-alpha-2	polymer	111	13251.8	2	UniProt (O75334) Pfam (PF25526)	Homo sapiens (human)	Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2,PTPRF-interacting protein alpha-2
3	E, F, G (A, B, D)	water	water		18.0	20	Chemie (HOH)

Sequence modifications

A, B: 1166 - 1334 (UniProt: A0A8I6GEN0)

PDB	External Database	Details
His 1160	-	expression tag
Met 1161	-	expression tag
Gly 1162	-	expression tag
Ser 1163	-	expression tag
Glu 1164	-	expression tag
Phe 1165	-	expression tag

C, D: 300 - 404 (UniProt: O75334)

PDB	External Database	Details
Gly 294	-	expression tag
Pro 295	-	expression tag
Gly 296	-	expression tag
Ser 297	-	expression tag
Glu 298	-	expression tag
Phe 299	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	64962.1
All*	Total formula weight	64962.1

*Water molecules are not included.