8Z02

CoA bound to human GTP-specific succinyl-CoA synthetase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial	polymer	321	34250.1	1	UniProt (P53597) Pfam (PF02629) Pfam (PF00549)	Homo sapiens (human)	Succinyl-CoA synthetase subunit alpha,SCS-alpha
2	B (B)	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial	polymer	395	42627.8	1	UniProt (Q96I99) Pfam (PF08442) Pfam (PF00549)	Homo sapiens (human)	GTP-specific succinyl-CoA synthetase subunit beta,G-SCS,GTPSCS,Succinyl-CoA synthetase beta-G chain,SCS-betaG
3	C (A)	COENZYME A	non-polymer		767.5	1	Chemie (COA)
4	D (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	E, F (A, B)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A: 2 - 306 (UniProt: P53597)

PDB	External Database	Details
Met 1	-	initiating methionine
Glu 307	-	expression tag
Asn 308	-	expression tag
Leu 309	-	expression tag
Tyr 310	-	expression tag
Phe 311	-	expression tag
Gln 312	-	expression tag
Gly 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag

B: 2 - 395 (UniProt: Q96I99)

PDB	External Database	Details
Met 1	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76877.9
Non-Polymers*	Number of molecules	2
	Total formula weight	862.5
All*	Total formula weight	77740.4

*Water molecules are not included.