8YYV

A dimeric STAT1-DNA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Signal transducer and activator of transcription 1-alpha/beta	polymer	776	90766.1	1	UniProt (P42224) Pfam (PF02865) Pfam (PF01017) Pfam (PF02864) Pfam (PF21354) Pfam (PF00017) Pfam (PF12162)	Homo sapiens (human)	Transcription factor ISGF-3 components p91/p84
2	B (C)	DNA (5'-D(P*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*GP*C)-3')	polymer	18	5475.6	1		Homo sapiens
3	C (B)	DNA (5'-D(P*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*TP*G)-3')	polymer	18	5555.6	1		Homo sapiens

Sequence modifications

A: 1 - 750 (UniProt: P42224)

PDB	External Database	Details
Met -25	-	initiating methionine
Asn -24	-	expression tag
His -23	-	expression tag
Lys -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	101797.3
All*	Total formula weight	101797.3

*Water molecules are not included.